Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC16A3 | O15427 | 1/20 | 0.56 |
| ▸ | MAOB | P27338 | 1/20 | 0.55 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.54 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | PLAU | P00749 | 1/20 | 0.52 |
| ▸ | PLAT | P00750 | 1/20 | 0.52 |
| ▸ | MDH2 | P40926 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.51 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.51 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.51 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.51 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1681413 | 0.88 | MAOB (0.51) | SLC16A3MAOBALOX5MRGPRX4ALDH1A1 | |
| SCHEMBL1681386 | 0.85 | WDR5 (0.53) | SLC16A3MRGPRX4ALDH1A1SMN1; SMN2NR4A2 | |
| SCHEMBL29043356 | 0.85 | PTGER1 (0.47) | SLC16A3MAOBMRGPRX4ALDH1A1MCL1 | |
| SCHEMBL6414966 | 0.84 | MRGPRX4 (0.60) | SLC16A3MAOBALOX5MRGPRX4ALDH1A1 | |
| SCHEMBL23796860 | 0.81 | MEN1 (0.65) | SLC16A3MAOBALOX5ALDH1A1HPGD | |
| SCHEMBL7161222 | 0.81 | MAOB (0.65) | SLC16A3MAOBALOX5ALDH1A1HPGD | |
| SCHEMBL3424839 | 0.80 | ALDH1A1 (0.55) | MAOBALDH1A1HPGDSMN1; SMN2NR4A2 | |
| SCHEMBL14302686 | 0.80 | MAOB (0.60) | SLC16A3MAOBALOX5ALDH1A1HPGD | |
| SCHEMBL1519064 | 0.79 | MAOB (0.77) | SLC16A3MAOBALDH1A1HPGDMDH2 | |
| SCHEMBL4756552 | 0.79 | MAOB (0.63) | SLC16A3MAOBALOX5ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8822515-B2 | Heterocyclic benzoxazole compositions as inhibitors of hepatitis C virus | UNIVERSITY OF MARYLAND, BALTIMORE COUNTY (US) | 2014-09-02 | — | — | US | disclosed |
| US-20120208856-A1 | Heterocyclic Benzoxazole Compositions as Inhibitors of Hepatitis C Virus | UNIVERSITY OF MARYLAND, BALTIMORE COUNTY | 2012-08-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120208856-A1 | Heterocyclic Benzoxazole Compositions as Inhibitors of Hepatitis C Virus | HAVCR2, CYP3A7, CYP2C9 | SLC16A3 3381/4885MAOB 602/4885ALOX5 1008/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.