SCHEMBL14001674

SCHEMBL14001674

COc1ccc(N=Nc2cc(C)c(N=Nc3cc(C)c(N=Nc4c(SOOO)cc5cc(Nc6ccc(N)c(S(=O)(=O)O)c6)ccc5c4O)cc3C)cc2C)c(S(=O)(=O)O)c1

nearest known ligand 0.45

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
▸ ENPP2 Q13822 11/20 0.45
▸ SUMO2 P61956 1/20 0.38
▸ SUMO1 P63165 1/20 0.38
▸ SENP7 Q9BQF6 1/20 0.38
▸ SENP3 Q9H4L4 1/20 0.38
▸ SENP2 Q9HC62 1/20 0.38
▸ SENP1 Q9P0U3 1/20 0.38
▸ CD40 P25942 1/20 0.38
▸ CD40LG P29965 1/20 0.38
▸ ALDH1A1 P00352 1/20 0.38
▸ HIF1A Q16665 1/20 0.38
▸ CTDSP1 Q9GZU7 1/20 0.38
▸ CARM1 Q86X55 1/20 0.37
▸ PRMT1 Q99873 1/20 0.37
▸ PHLPP2 Q6ZVD8 1/20 0.37
▸ MEN1 O00255 1/20 0.35
▸ HTT P42858 1/20 0.35
▸ KMT2A Q03164 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13088669 0.93 ENPP2 (0.49) ENPP2SUMO2SUMO1SENP7SENP3
SCHEMBL13088675 0.92 ENPP2 (0.48) ENPP2SUMO2SUMO1SENP7SENP3
SCHEMBL11911523 0.91 ENPP2 (0.55) ENPP2CD40CD40LGALDH1A1HIF1A
SCHEMBL14001676 0.91 ENPP2 (0.53) ENPP2SUMO2SUMO1SENP7SENP3
SCHEMBL13088672 0.90 ENPP2 (0.55) ENPP2CD40CD40LGALDH1A1HIF1A
SCHEMBL13088668 0.90 ENPP2 (0.55) ENPP2CD40CD40LGALDH1A1HIF1A
SCHEMBL14001677 0.89 ENPP2 (0.51) ENPP2CD40CD40LGALDH1A1HIF1A
SCHEMBL15935780 0.89 ENPP2 (0.56) ENPP2SUMO2SUMO1SENP7SENP3
SCHEMBL14001679 0.88 ENPP2 (0.60) ENPP2CD40CD40LGALDH1A1HIF1A
SCHEMBL13868539 0.87 ENPP2 (0.47) ENPP2CD40CD40LGALDH1A1HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7445822-B2 Azo compounds and dye-type polarizing films or plates containing the same NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2008-11-04 — — US disclosed
US-20080094549-A1 Azo Compounds And Dye-Type Polarizing Films Or Plates Containing The Same NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2008-04-24 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080094549-A1 Azo Compounds And Dye-Type Polarizing Films Or Plates Containing The Same CRY1, SCO2, SPR ENPP2 1986/4885SUMO2 3341/4885SUMO1 1973/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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