Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.38 |
| ▸ | HSP90B1 | P14625 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.30 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11913423 | 0.92 | HSP90AA1 (0.33) | HSP90AA1HSP90B1 | |
| SCHEMBL11918138 | 0.90 | HSP90AA1 (0.32) | HSP90AA1HSP90B1KMT2AMEN1TP53 | |
| SCHEMBL11903201 | 0.86 | P2RX7 (0.39) | HSP90AA1P2RX7CYP1A2 | |
| SCHEMBL11913430 | 0.86 | MEP1B (0.34) | KMT2AMEN1HPGDALDH1A1P2RX7 | |
| SCHEMBL11903393 | 0.83 | HSP90AA1 (0.33) | HSP90AA1 | |
| SCHEMBL1653947 | 0.83 | GRIN2B (0.32) | ALDH1A1KDM4EMEP1B | |
| SCHEMBL11902642 | 0.81 | ALDH1A1 (0.34) | KMT2AALDH1A1KDM4EPOLBMEP1B | |
| SCHEMBL11902965 | 0.81 | HTT (0.39) | KMT2AMEN1HPGDALDH1A1KDM4E | |
| SCHEMBL11903073 | 0.80 | TAS1R3 (0.34) | KMT2AALDH1A1KDM4EMEP1B | |
| SCHEMBL11903251 | 0.79 | HSP90AA1 (0.38) | HSP90AA1P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120202690-A1 | HERBICIDAL COMPOUNDS | SYNGENTA LIMITED (US) | 2012-08-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120202690-A1 | HERBICIDAL COMPOUNDS | DDT, HAO2, HAAO | HSP90AA1 853/4885HSP90B1 1301/4885KMT2A 1798/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.