Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 2/20 | 0.32 |
| ▸ | FEN1 | P39748 | 2/20 | 0.32 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.32 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.30 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.30 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11913426 | 0.86 | AMY1A (0.32) | ALOX5APFEN1HSP90AB1PDGFRBAMY1A | |
| SCHEMBL11918154 | 0.85 | ALOX5AP (0.31) | ALOX5APFEN1PDGFRB | |
| SCHEMBL11918051 | 0.77 | DYRK1A (0.38) | HSP90AB1DYRK1A | |
| SCHEMBL11918078 | 0.72 | ALOX5AP (0.31) | ALOX5APFEN1PDGFRB | |
| SCHEMBL11902825 | 0.71 | KMO (0.43) | DYRK1A | |
| SCHEMBL1654723 | 0.71 | NR4A2 (0.36) | PDGFRB | |
| SCHEMBL11918057 | 0.69 | ALOX5AP (0.32) | ALOX5APFEN1 | |
| SCHEMBL17452532 | 0.69 | EGFR (0.36) | — | |
| SCHEMBL1656974 | 0.69 | GLP1R (0.35) | — | |
| SCHEMBL11903329 | 0.68 | MEP1B (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120202690-A1 | HERBICIDAL COMPOUNDS | SYNGENTA LIMITED (US) | 2012-08-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120202690-A1 | HERBICIDAL COMPOUNDS | DDT, HAO2, HAAO | ALOX5AP 996/4885FEN1 2445/4885HSP90AB1 607/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.