Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 2/20 | 0.43 |
| ▸ | PRKAG1 | P54619 | 11/20 | 0.38 |
| ▸ | PRKAA1 | Q13131 | 11/20 | 0.38 |
| ▸ | PRKAB1 | Q9Y478 | 11/20 | 0.38 |
| ▸ | PRKAB2 | O43741 | 9/20 | 0.38 |
| ▸ | PRKAA2 | P54646 | 9/20 | 0.38 |
| ▸ | PRKAG3 | Q9UGI9 | 9/20 | 0.38 |
| ▸ | PRKAG2 | Q9UGJ0 | 9/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CDK9 | P50750 | 2/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.34 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.34 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.34 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.34 |
| ▸ | EIF4E | P06730 | 1/20 | 0.34 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.33 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.33 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1654723 | 0.92 | NR4A2 (0.36) | KMOPRKAG1PRKAA1PRKAB1PRKAB2 | |
| SCHEMBL1656974 | 0.88 | GLP1R (0.35) | ALDH1A1MEP1B | |
| SCHEMBL11903329 | 0.87 | MEP1B (0.33) | KMOPRKAG1PRKAA1PRKAB1PRKAB2 | |
| SCHEMBL11902585 | 0.85 | DHODH (0.39) | HSD17B10 | |
| SCHEMBL11913426 | 0.85 | AMY1A (0.32) | PRKAG1PRKAA1PRKAB1PRKAB2PRKAA2 | |
| SCHEMBL11903304 | 0.84 | ABCB11 (0.34) | KDM4EALDH1A1MEP1B | |
| SCHEMBL11902297 | 0.84 | PTGES (0.36) | ALDH1A1MEP1B | |
| SCHEMBL11903206 | 0.84 | PKM (0.35) | PRKAG1PRKAA1PRKAB1PRKAB2PRKAA2 | |
| SCHEMBL11913427 | 0.83 | SMN1; SMN2 (0.37) | KDM4EALDH1A1 | |
| SCHEMBL11902294 | 0.83 | PTGES (0.33) | PRKAG1PRKAA1PRKAB1MEP1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120202690-A1 | HERBICIDAL COMPOUNDS | SYNGENTA LIMITED (US) | 2012-08-09 | — | — | US | disclosed |
| US-20120202690-A1 | HERBICIDAL COMPOUNDS | SYNGENTA LIMITED (US) | 2012-08-09 | — | — | US | disclosed |
| US-20120202690-A1 | HERBICIDAL COMPOUNDS | SYNGENTA LIMITED (US) | 2012-08-09 | — | — | US | disclosed |
| WO-2011045561-A2 | HERBICIDAL COMPOUNDS | SYNGENTA LIMITED (GB) | 2011-04-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120202690-A1 | HERBICIDAL COMPOUNDS | DDT, HAO2, HAAO | KMO 89/4885PRKAG1 2566/4885PRKAA1 680/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.