Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 2/20 | 0.33 |
| ▸ | GCGR | P47871 | 2/20 | 0.32 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.31 |
| ▸ | EPHX1 | P07099 | 5/20 | 0.31 |
| ▸ | KDM4A | O75164 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | CRHBP | P24387 | 1/20 | 0.30 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.30 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.30 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8986320 | 0.86 | MAPT (0.36) | BCHEGCGRHSD17B2NPC1MAPT | |
| SCHEMBL11920184 | 0.86 | AKR1C3 (0.36) | NPC1MAPTRAB9ASRD5A2 | |
| SCHEMBL11921695 | 0.85 | MAPT (0.34) | BCHEGCGRHSD17B2NPC1MAPT | |
| SCHEMBL8986337 | 0.85 | MAPT (0.34) | BCHEGCGRHSD17B2NPC1MAPT | |
| SCHEMBL8986351 | 0.83 | BCHE (0.35) | BCHEGCGRNPC1MAPTRAB9A | |
| SCHEMBL11920183 | 0.77 | GCGR (0.34) | GCGRNPC1RAB9ASRD5A2 | |
| SCHEMBL8986294 | 0.76 | GCGR (0.36) | BCHEGCGRNPC1RAB9ASRD5A2 | |
| SCHEMBL14282584 | 0.74 | AKR1C3 (0.44) | NPC1MAPTRAB9ASRD5A2 | |
| SCHEMBL13328292 | 0.71 | ALDH1A1 (0.47) | NPC1RAB9ASRD5A2USP2 | |
| SCHEMBL8986301 | 0.68 | AKR1C3 (0.38) | NPC1MAPTRAB9ASRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120209009-A1 | SYNTHETIC ROUTE TO ABCD-PORPHYRINS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2012-08-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120209009-A1 | SYNTHETIC ROUTE TO ABCD-PORPHYRINS | ABCB7, ALAD, SLC39A14 | BCHE 3168/4885GCGR 4832/4885HSD17B2 1258/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.