Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | ESRRG | P62508 | 1/20 | 0.31 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 3/20 | 0.31 |
| ▸ | RAB9A | P51151 | 3/20 | 0.31 |
| ▸ | PKM | P14618 | 2/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.30 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8986294 | 0.79 | GCGR (0.36) | GCGRSMN1; SMN2HPGDALDH1A1LMNA | |
| SCHEMBL11920182 | 0.77 | BCHE (0.33) | GCGRSRD5A2NPC1RAB9A | |
| SCHEMBL8986320 | 0.75 | MAPT (0.36) | GCGRALDH1A1LMNASRD5A2NPC1 | |
| SCHEMBL11921695 | 0.73 | MAPT (0.34) | GCGRALDH1A1LMNASRD5A2NPC1 | |
| SCHEMBL8986337 | 0.73 | MAPT (0.34) | GCGRALDH1A1LMNAESRRGSRD5A2 | |
| SCHEMBL8986351 | 0.71 | BCHE (0.35) | GCGRSMN1; SMN2ALDH1A1LMNAESRRG | |
| SCHEMBL13621651 | 0.67 | SRD5A2 (0.63) | SMN1; SMN2HPGDALDH1A1LMNAGAA | |
| SCHEMBL13328292 | 0.64 | ALDH1A1 (0.47) | SMN1; SMN2HPGDALDH1A1LMNAGAA | |
| SCHEMBL7472850 | 0.61 | KDM4E (0.44) | SMN1; SMN2HPGDALDH1A1LMNAGAA | |
| SCHEMBL8904574 | 0.61 | NPC1 (0.42) | SMN1; SMN2HPGDALDH1A1LMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120209009-A1 | SYNTHETIC ROUTE TO ABCD-PORPHYRINS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2012-08-16 | — | — | US | disclosed |
| US-20120209009-A1 | SYNTHETIC ROUTE TO ABCD-PORPHYRINS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2012-08-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120209009-A1 | SYNTHETIC ROUTE TO ABCD-PORPHYRINS | ABCB7, ALAD, SLC39A14 | GCGR 4832/4885SMN1; SMN2 3566/4885HPGD 284/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.