Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.58 |
| ▸ | PKM | P14618 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.54 |
| ▸ | NTRK1 | P04629 | 4/20 | 0.50 |
| ▸ | NTRK2 | Q16620 | 4/20 | 0.50 |
| ▸ | USP2 | O75604 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2665689 | 0.80 | TDP1 (0.63) | TDP1PKMKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL18062419 | 0.78 | NPC1 (0.66) | TDP1PKMKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL162869 | 0.76 | NPC1 (0.72) | TDP1KDM4EL3MBTL1NPC1RAB9A | |
| SCHEMBL21240899 | 0.75 | KDM4E (0.64) | TDP1PKMKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL28327199 | 0.75 | NPC1 (0.66) | TDP1PKMKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL507242 | 0.75 | RAB9A (0.66) | TDP1KDM4EALDH1A1L3MBTL1NPC1 | |
| Hydrochloric Acid SCHEMBL6381967 | 0.74 | NPC1 (0.70) | TDP1KDM4EL3MBTL1NPC1RAB9A | |
| SCHEMBL13024512 | 0.73 | KDM4E (0.51) | TDP1PKMKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL19900857 | 0.72 | NPC1 (0.62) | TDP1PKMKDM4EALDH1A1L3MBTL1 | |
| Azobenzene SCHEMBL11783356 | 0.71 | TDP1 (0.52) | TDP1PKMKDM4EALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110046153-A1 | Medicaments | MOTAC NEUROSCIENCE LIMITED (GB) | 2011-02-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110046153-A1 | Medicaments | MTNR1A, SIGMAR1, OPRK1 | TDP1 887/4885PKM 1783/4885KDM4E 4433/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.