Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | FPR2 | P25090 | 3/20 | 0.38 |
| ▸ | ALPG | P10696 | 2/20 | 0.36 |
| ▸ | PLAA | Q9Y263 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA3 | P07451 | 1/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
| ▸ | CA6 | P23280 | 1/20 | 0.36 |
| ▸ | CA5A | P35218 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.36 |
| ▸ | ALPL | P05186 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19033087 | 0.95 | LMNA (0.36) | LMNAFPR2ALPGPLAACA12 | |
| SCHEMBL10260904 | 0.87 | LMNA (0.39) | LMNAFPR2ALPGPLAACA12 | |
| SCHEMBL10261857 | 0.87 | FPR2 (0.45) | LMNAFPR2ALPGPLAAALPL | |
| SCHEMBL11936765 | 0.83 | RAB9A (0.39) | LMNAFPR2ALPGPLAACA12 | |
| SCHEMBL10261285 | 0.83 | ALPG (0.35) | LMNAFPR2ALPGPLAACA12 | |
| SCHEMBL13764517 | 0.77 | LMNA (0.39) | LMNAFPR2SMN1; SMN2ALDH1A1L3MBTL1 | |
| SCHEMBL11930756 | 0.77 | LMNA (0.39) | LMNASMN1; SMN2ALDH1A1L3MBTL1OPRK1 | |
| SCHEMBL13310652 | 0.74 | ALPG (0.39) | FPR2ALPGPLAACA12CA1 | |
| SCHEMBL19033089 | 0.72 | ALDH1A1 (0.37) | LMNASMN1; SMN2ALDH1A1L3MBTL1TSHR | |
| SCHEMBL10261291 | 0.72 | LMNA (0.48) | LMNASMN1; SMN2ALDH1A1L3MBTL1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2648766-B1 | PSMA-TARGETED DENDRIMERS | MOLECULAR INSIGHT PHARM INC (US) | 2018-04-18 | — | — | EP | disclosed |
| US-8211401-B2 | Technetium- and rhenium-bis(heteroaryl) complexes and methods of use thereof for inhibiting PSMA | MOLECULAR INSIGHT PHARMACEUTICALS, INC. (US) | 2012-07-03 | — | — | US | disclosed |
| US-8211401-B2 | Technetium- and rhenium-bis(heteroaryl) complexes and methods of use thereof for inhibiting PSMA | MOLECULAR INSIGHT PHARMACEUTICALS, INC. (US) | 2012-07-03 | — | — | US | disclosed |