Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 6/20 | 0.71 |
| ▸ | ADORA2A | P29274 | 5/20 | 0.71 |
| ▸ | SQOR | Q9Y6N5 | 6/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.66 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.64 |
| ▸ | HPGD | P15428 | 3/20 | 0.64 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.64 |
| ▸ | PPARG | P37231 | 1/20 | 0.64 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.64 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.64 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14582056 | 0.89 | ADORA1 (0.60) | ADORA1ADORA2ASQORL3MBTL1MAPK1 | |
| Bromide SCHEMBL4074769 | 0.87 | L3MBTL1 (0.68) | ADORA1ADORA2ASQORL3MBTL1MAPK1 | |
| SCHEMBL14176622 | 0.86 | KDM4E (0.77) | ADORA1ADORA2ASQORL3MBTL1MAPK1 | |
| SCHEMBL4064211 | 0.86 | L3MBTL1 (0.71) | ADORA1ADORA2ASQORL3MBTL1MAPK1 | |
| Bromide SCHEMBL4074767 | 0.83 | L3MBTL1 (0.68) | ADORA1ADORA2ASQORL3MBTL1MAPK1 | |
| SCHEMBL4911494 | 0.83 | ADORA1 (1.00) | ADORA1ADORA2AL3MBTL1KDM4EHPGD | |
| SCHEMBL31120336 | 0.83 | ADORA1 (1.00) | ADORA1ADORA2AL3MBTL1KDM4EHPGD | |
| SCHEMBL22208383 | 0.82 | ADORA1 (1.00) | ADORA1ADORA2AL3MBTL1KDM4EHPGD | |
| SCHEMBL31120420 | 0.82 | ADORA1 (1.00) | ADORA1ADORA2AL3MBTL1KDM4EHPGD | |
| SCHEMBL31120383 | 0.82 | ADORA1 (1.00) | ADORA1ADORA2AL3MBTL1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120277252-A1 | Antibacterial Agents and Methods of Use Thereof | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2012-11-01 | — | — | US | disclosed |
| US-8227616-B2 | Cyanopyridine antibacterial agents and methods of use thereof | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2012-07-24 | — | — | US | disclosed |
| US-20100261763-A1 | ANTIBACTERIAL AGENTS AND METHODS OF USE THEREOF | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2010-10-14 | — | — | US | disclosed |
| US-7737164-B2 | Cyanopyridine antibacterial agents | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2010-06-15 | — | — | US | disclosed |
| US-20080009528-A1 | ANTIBACTERIAL AGENTS AND RELATED SCREENING METHODS USING SMALL MOLECULE MACROARRAYS | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2008-01-10 | — | — | US | disclosed |
| US-20070128658-A1 | FLUORESCENT DYES, METHODS AND USES THEREOF | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2007-06-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120277252-A1 | Antibacterial Agents and Methods of Use Thereof | FDPS, ABCG2, DUT | ADORA1 3317/4885ADORA2A 4136/4885SQOR 98/4885 |
| US-20080009528-A1 | ANTIBACTERIAL AGENTS AND RELATED SCREENING METHODS USING SMALL MOLECULE MACROARRAYS | PCNA, ABCG2, API5 | ADORA1 3358/4885ADORA2A 3726/4885SQOR 906/4885 |
| US-20100261763-A1 | ANTIBACTERIAL AGENTS AND METHODS OF USE THEREOF | FDPS, CYP3A5, ABCG2 | ADORA1 3520/4885ADORA2A 4209/4885SQOR 123/4885 |
| US-20070128658-A1 | FLUORESCENT DYES, METHODS AND USES THEREOF | DHX15, DHX35, DUT | ADORA1 2602/4885ADORA2A 2011/4885SQOR 304/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.