Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTK | P33981 | 4/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | JAK2 | O60674 | 5/20 | 0.34 |
| ▸ | JAK1 | P23458 | 5/20 | 0.34 |
| ▸ | TYK2 | P29597 | 5/20 | 0.34 |
| ▸ | JAK3 | P52333 | 3/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | ELOVL6 | Q9H5J4 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ORAI1 | Q96D31 | 2/20 | 0.32 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.31 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15059546 | 1.00 | TTK (0.36) | TTKCA1CA2JAK2JAK1 | |
| SCHEMBL12846262 | 0.94 | TTK (0.33) | TTKCA1CA2JAK2JAK1 | |
| SCHEMBL1795057 | 0.93 | CA1 (0.32) | TTKCA1CA2HSD11B1LMNA | |
| SCHEMBL740369 | 0.93 | CA1 (0.34) | CA1CA2ELOVL6LMNAORAI1 | |
| SCHEMBL119374 | 0.92 | PTGES (0.35) | TTKCA1CA2ELOVL6LMNA | |
| SCHEMBL2148165 | 0.91 | CNR1 (0.35) | LMNA | |
| Hydrochloric Acid SCHEMBL738507 | 0.91 | CA1 (0.33) | CA1CA2ELOVL6LMNAORAI1 | |
| SCHEMBL737408 | 0.91 | EGLN1 (0.36) | CA1CA2ELOVL6LMNAORAI1 | |
| SCHEMBL28908172 | 0.91 | CA1 (0.35) | CA1CA2ORAI1 | |
| SCHEMBL30233680 | 0.90 | CASP1 (0.39) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013092460-A1 | CYCLIC BISOXIME MICROBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2013-06-27 | — | — | WO | disclosed |