Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | PTGES | O14684 | 1/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.31 |
| ▸ | ORAI1 | Q96D31 | 4/20 | 0.31 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ELOVL6 | Q9H5J4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fluralaner SCHEMBL29362559 | 1.00 | CA1 (0.32) | CA1CA2PTGESHDAC4ORAI1 | |
| Fluralaner SCHEMBL8513367 | 1.00 | CA1 (0.32) | CA1CA2PTGESHDAC4ORAI1 | |
| Fluralaner SCHEMBL29399660 | 1.00 | CA1 (0.32) | CA1CA2PTGESHDAC4ORAI1 | |
| Fluralaner SCHEMBL121934 | 1.00 | CA1 (0.32) | CA1CA2PTGESHDAC4ORAI1 | |
| SCHEMBL23546689 | 0.95 | GABRA5 (0.31) | CA1CA2PTGESGABRA5 | |
| SCHEMBL22919822 | 0.94 | PTGES (0.33) | PTGESHDAC4KDM4E | |
| SCHEMBL120084 | 0.94 | PTGES (0.33) | PTGESHDAC4KDM4E | |
| SCHEMBL15999841 | 0.94 | PTGES (0.31) | CA1CA2PTGESGABRA5LMNA | |
| SCHEMBL119374 | 0.94 | PTGES (0.35) | CA1CA2PTGESORAI1GABRA5 | |
| SCHEMBL23530405 | 0.93 | LMNA (0.32) | CA1CA2PTGESORAI1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250287955-A1 | METHODS OF PROTECTING A PLANT FROM INSECT PESTS | Novonesis Plant Biosolutions A/S (DK) | 2025-09-18 | — | — | US | disclosed |
| US-20240239759-A1 | ISOXAZOLINE COMPOSITIONS AND THEIR USE AS ANTIPARASITICS | INTERVET INC. (US) | 2024-07-18 | — | — | US | disclosed |
| US-11530187-B2 | Method for producing (5S)-4-[5-(3,5-dichlorophenyl)-5-(trifluoromethyl)-4H-isoxazol-3-yl]-2-methyl-benzoic acid | INTERVET INC. (US) | 2022-12-20 | — | — | US | disclosed |
| WO-2022258797-A1 | TICK CONTROL METHODS | INTERVET INTERNATIONAL B.V. (NL) | 2022-12-15 | — | — | WO | disclosed |
| US-20210251238-A1 | METHODS OF PROTECTING A PLANT FROM INSECT PESTS | NOVOZYMES BIOAG A/S (DK) | 2021-08-19 | — | — | US | disclosed |
| WO-2021122513-A1 | COMPOSITION FOR LICE CONTROL | INTERVET INTERNATIONAL B.V. (NL) | 2021-06-24 | — | — | WO | disclosed |
| WO-2021122521-A1 | COMPOSITION FOR LICE CONTROL IN POULTRY | INTERVET INTERNATIONAL B.V. (NL) | 2021-06-24 | — | — | WO | disclosed |
| EP-3473101-B1 | ISOXAZOLINE COMPOSITIONS AND THEIR USE AS ANTIPARASITICS FOR FELINES | INTERVET INT BV (NL) | 2021-05-12 | — | — | EP | disclosed |
| EP-3801017-A1 | METHODS OF PROTECTING A PLANT FROM INSECT PESTS | Novozymes Bioag A/S (DK) | 2021-04-14 | — | — | EP | disclosed |
| US-20210061775-A1 | ISOXAZOLINE COMPOSITIONS AND THEIR USE AS ANTIPARASITICS | INTERVET INC. (US) | 2021-03-04 | — | — | US | disclosed |
| EP-2641901-A1 | Novel microbiocides | Syngenta Participations AG. (CH) | 2013-09-25 | — | — | EP | disclosed |
| WO-2013135617-A1 | METHODS AND COMPOSITIONS FOR PEST MANAGEMENT | SYNGENTA PARTICIPATIONS AG (CH) | 2013-09-19 | — | — | WO | disclosed |
| WO-2013092460-A1 | CYCLIC BISOXIME MICROBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2013-06-27 | — | — | WO | disclosed |
| WO-2013026900-A1 | PYRIDINE DERIVATIVES AS MICROBIOCIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2013-02-28 | — | — | WO | disclosed |
| WO-2012175474-A1 | 1,2,3 TRIAZOLE PESTICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2012-12-27 | — | — | WO | disclosed |
| WO-2012143395-A1 | 4,5-DIHYDRO-ISOXAZOLE DERIVATIVES AS FUNGICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2012-10-26 | — | — | WO | disclosed |
| WO-2012126881-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2012-09-27 | — | — | WO | disclosed |
| WO-2012107434-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2012-08-16 | — | — | WO | disclosed |
| WO-2012069601-A1 | SUBSTITUTED QUINAZOLINES AS FUNGICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2012-05-31 | — | — | WO | disclosed |
| WO-2009024541-A2 | ISOXAZOLINE COMPOSITIONS AND THEIR USE AS ANTIPARASITICS | INTERVET INTERNATIONAL B.V. (NL) | 2009-02-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11530187-B2 | Method for producing (5S)-4-[5-(3,5-dichlorophenyl)-5-(trifluoromethyl)-4H-isoxazol-3-yl]-2-methyl-benzoic acid | GABRA5, KDM5A, COX5A | CA1 1114/4885CA2 563/4885PTGES 1489/4885 |
| US-20210061775-A1 | ISOXAZOLINE COMPOSITIONS AND THEIR USE AS ANTIPARASITICS | PRDX5, TUBA3C, TUBA1C | CA1 1771/4885CA2 651/4885PTGES 2115/4885 |
| US-20240239759-A1 | ISOXAZOLINE COMPOSITIONS AND THEIR USE AS ANTIPARASITICS | PRDX5, TUBA3C, TUBA1C | CA1 1771/4885CA2 651/4885PTGES 2115/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.