SCHEMBL11941245

SCHEMBL11941245

c1ccc2c(c1)oc1c(-c3c4ccccc4c(-c4nccc5c4sc4ccccc45)c4ccccc34)nccc12

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.35
NPC1 O15118 2/20 0.35
ESR2 Q92731 2/20 0.34
ESR1 P03372 1/20 0.33
GPR3 P46089 1/20 0.33
DRD4 P21917 1/20 0.32
KMT2A Q03164 4/20 0.32
MEN1 O00255 3/20 0.32
LMNA P02545 2/20 0.32
USP2 O75604 1/20 0.32
HTT P42858 1/20 0.32
RAB9A P51151 1/20 0.32
KDM4E B2RXH2 2/20 0.32
ALDH1A1 P00352 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
LIMK1 P53667 2/20 0.31
CDK5 Q00535 1/20 0.31
CDK5R1 Q15078 1/20 0.31
KRAS P01116 1/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11941252 0.88 MEN1 (0.33) MAPTNPC1ESR2ESR1DRD4
SCHEMBL22409671 0.86 ALOX5 (0.34) MAPTNPC1ESR2ESR1GPR3
SCHEMBL11941220 0.85 GPR3 (0.45) MAPTGPR3KMT2AMEN1RAB9A
SCHEMBL11941239 0.85 ALDH1A1 (0.41) MAPTNPC1DRD4KMT2AMEN1
SCHEMBL22409673 0.82 ALOX5 (0.41) MAPTNPC1ESR2ESR1DRD4
SCHEMBL16141244 0.78 ALOX5 (0.44) MAPTNPC1ESR2ESR1PIK3CD
SCHEMBL19419237 0.76 ESR2 (0.46) MAPTESR2ESR1GPR3KMT2A
SCHEMBL17689908 0.76 ESR2 (0.49) MAPTESR2ESR1GPR3KMT2A
SCHEMBL18090104 0.76 PRKDC (0.32) PIK3CDPIK3CBPRKDC
SCHEMBL18090103 0.76 PRKDC (0.34) PIK3CDPIK3CBPRKDC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8415031-B2 Electron transporting compounds UNIVERSAL DISPLAY CORPORATION (US) 2013-04-09 US disclosed
US-8415031-B2 Electron transporting compounds UNIVERSAL DISPLAY CORPORATION (US) 2013-04-09 US disclosed
US-20120187381-A1 Electron Transporting Compounds UNIVERSAL DISPLAY CORPORATION (US) 2012-07-26 US disclosed
US-20120187381-A1 Electron Transporting Compounds UNIVERSAL DISPLAY CORPORATION (US) 2012-07-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120187381-A1 Electron Transporting Compounds SLC19A2, ABCB7, SLCO2B1 MAPT 2243/4885NPC1 1272/4885ESR2 1057/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.