SCHEMBL11941252

SCHEMBL11941252

c1ccc2c(c1)oc1c(-c3ccc(-c4c5ccccc5c(-c5ccc(-c6nccc7c6sc6ccccc67)cc5)c5ccccc45)cc3)nccc12

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
MAPT P10636 2/20 0.33
CSF1R P07333 1/20 0.33
PDGFRB P09619 1/20 0.33
KIT P10721 1/20 0.33
FLT3 P36888 1/20 0.33
HDAC6 Q9UBN7 1/20 0.33
NPC1 O15118 2/20 0.32
USP2 O75604 1/20 0.32
LMNA P02545 1/20 0.32
HTT P42858 1/20 0.32
RAB9A P51151 1/20 0.32
ESR2 Q92731 2/20 0.32
ALOX5 P09917 2/20 0.32
PRKDC P78527 1/20 0.31
MAPK14 Q16539 1/20 0.31
ESR1 P03372 1/20 0.31
TDO2 P48775 1/20 0.30
DRD4 P21917 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11941245 0.88 MAPT (0.35) MEN1KMT2AMAPTCSF1RPDGFRB
SCHEMBL11941238 0.86 MEN1 (0.41) MEN1KMT2AMAPTCSF1RPDGFRB
SCHEMBL11941221 0.86 GPR3 (0.39) MEN1KMT2AMAPTRAB9AALOX5
SCHEMBL11941219 0.82 TDO2 (0.42) MAPTNPC1RAB9AALOX5TDO2
SCHEMBL11941237 0.82 MAPT (0.44) MEN1KMT2AMAPTCSF1RPDGFRB
SCHEMBL22409671 0.82 ALOX5 (0.34) MEN1KMT2AMAPTNPC1USP2
SCHEMBL18090106 0.80 NPC1 (0.33) MAPTNPC1PRKDC
SCHEMBL18090111 0.80 PRKDC (0.30) ESR2PRKDCESR1
SCHEMBL18090102 0.79 ALOX5 (0.30) ALOX5PRKDC
SCHEMBL18090097 0.79 NPC1 (0.33) MAPTNPC1ALOX5PRKDC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8415031-B2 Electron transporting compounds UNIVERSAL DISPLAY CORPORATION (US) 2013-04-09 US disclosed
US-8415031-B2 Electron transporting compounds UNIVERSAL DISPLAY CORPORATION (US) 2013-04-09 US disclosed
US-20120187381-A1 Electron Transporting Compounds UNIVERSAL DISPLAY CORPORATION (US) 2012-07-26 US disclosed
US-20120187381-A1 Electron Transporting Compounds UNIVERSAL DISPLAY CORPORATION (US) 2012-07-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120187381-A1 Electron Transporting Compounds SLC19A2, ABCB7, SLCO2B1 MEN1 3293/4885KMT2A 2879/4885MAPT 2243/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.