Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.58 |
| ▸ | TSHR | P16473 | 4/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | ESR1 | P03372 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.51 |
| ▸ | KDR | P35968 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 2/20 | 0.50 |
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA7 | P43166 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | CASP1 | P29466 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12865768 | 0.93 | TSHR (0.58) | MAPTTSHRTDP1RAB9AESR1 | |
| SCHEMBL15068275 | 0.89 | MAPT (0.64) | MAPTTSHRTDP1RAB9AESR1 | |
| SCHEMBL12908145 | 0.88 | MAPT (0.77) | MAPTTSHRTDP1RAB9AALDH1A1 | |
| SCHEMBL28753801 | 0.85 | CA1 (0.63) | MAPTTSHRTDP1RAB9AESR1 | |
| SCHEMBL9667206 | 0.84 | LMNA (0.70) | TSHRTDP1RAB9AESR1ALDH1A1 | |
| SCHEMBL14490727 | 0.83 | HTT (0.70) | MAPTTSHRTDP1RAB9AALDH1A1 | |
| SCHEMBL23522273 | 0.83 | MAPT (0.58) | MAPTTSHRTDP1RAB9AESR1 | |
| SCHEMBL680463 | 0.83 | ALDH1A1 (0.72) | MAPTTSHRTDP1RAB9AESR1 | |
| SCHEMBL16640624 | 0.83 | MAPT (0.60) | MAPTTSHRTDP1RAB9AESR1 | |
| SCHEMBL19004809 | 0.82 | SMN1; SMN2 (0.54) | MAPTTSHRTDP1RAB9AESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9458354-B2 | Polyurethane dispersions and methods of making and using same | Resinate Technologies, Inc. (US) | 2016-10-04 | — | — | US | disclosed |
| US-9458354-B2 | Polyurethane dispersions and methods of making and using same | Resinate Technologies, Inc. (US) | 2016-10-04 | — | — | US | disclosed |
| US-20140107374-A1 | FUNCTIONALIZED POLYETHYLENE TEREPHTHALATE POLYMERS, FUNCTIONALIZED DERIVATIVE POLYMERS OF POLYETHYLENE TEREPHTHALATE, METHODS OF MAKING AND USING SAME | FELICE KRISTOPHER M (US) | 2014-04-17 | — | — | US | disclosed |
| US-20140107374-A1 | FUNCTIONALIZED POLYETHYLENE TEREPHTHALATE POLYMERS, FUNCTIONALIZED DERIVATIVE POLYMERS OF POLYETHYLENE TEREPHTHALATE, METHODS OF MAKING AND USING SAME | FELICE KRISTOPHER M (US) | 2014-04-17 | — | — | US | disclosed |
| US-20120259061-A1 | Polyurethane Dispersions and Methods of Making and Using Same | RESINATE MATERIALS GROUP, INC. | 2012-10-11 | — | — | US | disclosed |
| US-20120190800-A1 | FUNCTIONALIZED POLYETHYLENE TEREPHTHALATE POLYMERS, FUNCTIONALIZED DERIVATIVE POLYMERS OF POLYETHYLENE TEREPHTHALATE, METHODS OF MAKING AND USING SAME | FELICE KRISTOPHER M (US) | 2012-07-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140107374-A1 | FUNCTIONALIZED POLYETHYLENE TEREPHTHALATE POLYMERS, FUNCTIONALIZED DERIVATIVE POLYMERS OF POLYETHYLENE TEREPHTHALATE, METHODS OF MAKING AND USING SAME | PIGO, ESD, FTO | MAPT 1087/4885TSHR 636/4885TDP1 908/4885 |
| US-20120190800-A1 | FUNCTIONALIZED POLYETHYLENE TEREPHTHALATE POLYMERS, FUNCTIONALIZED DERIVATIVE POLYMERS OF POLYETHYLENE TEREPHTHALATE, METHODS OF MAKING AND USING SAME | PIGO, ESD, FTO | MAPT 1087/4885TSHR 636/4885TDP1 908/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.