Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 9/20 | 0.83 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.83 |
| ▸ | HTT | P42858 | 5/20 | 0.83 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.83 |
| ▸ | TSHR | P16473 | 2/20 | 0.83 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.83 |
| ▸ | TP53 | P04637 | 1/20 | 0.83 |
| ▸ | DNM2 | P50570 | 7/20 | 0.62 |
| ▸ | MAPT | P10636 | 8/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.60 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.58 |
| ▸ | GLA | P06280 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.56 |
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23094149 | 0.91 | LMNA (1.00) | LMNASMN1; SMN2HTTALDH1A1TSHR | |
| SCHEMBL13329877 | 0.86 | LMNA (0.77) | LMNASMN1; SMN2HTTALDH1A1TSHR | |
| SCHEMBL13329940 | 0.85 | ESR1 (0.64) | LMNASMN1; SMN2HTTALDH1A1TSHR | |
| SCHEMBL13329946 | 0.85 | DNM2 (0.81) | LMNASMN1; SMN2HTTALDH1A1TSHR | |
| SCHEMBL13329945 | 0.85 | DNM2 (0.81) | LMNASMN1; SMN2HTTALDH1A1TSHR | |
| SCHEMBL13329988 | 0.84 | LMNA (0.59) | LMNASMN1; SMN2HTTALDH1A1TSHR | |
| SCHEMBL1194281 | 0.83 | DNM2 (0.78) | LMNASMN1; SMN2HTTALDH1A1TSHR | |
| SCHEMBL13329951 | 0.82 | DNM2 (0.77) | LMNASMN1; SMN2HTTALDH1A1TSHR | |
| SCHEMBL13329900 | 0.81 | KCNH3 (0.66) | LMNASMN1; SMN2HTTALDH1A1TSHR | |
| SCHEMBL13329899 | 0.81 | KCNH3 (0.66) | LMNASMN1; SMN2HTTALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7722893-B2 | Use of substitute 2,4-bis (alkylamino) pyrimidines or quinzolines as antimicrobials | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2010-05-25 | — | — | US | disclosed |
| US-7722893-B2 | Use of substitute 2,4-bis (alkylamino) pyrimidines or quinzolines as antimicrobials | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2010-05-25 | — | — | US | disclosed |