Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 1/20 | 0.43 |
| ▸ | WDR5 | P61964 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 2/20 | 0.37 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | APOB | P04114 | 3/20 | 0.35 |
| ▸ | MTTP | P55157 | 3/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3645819 | 0.93 | PDPK1 (0.48) | PDPK1WDR5ACHEKDM1AMAOA | |
| SCHEMBL3645250 | 0.87 | PDPK1 (0.53) | PDPK1ACHEKDM1AMAOAMAOB | |
| SCHEMBL11948888 | 0.81 | HTR7 (0.39) | WDR5ACHEAPOBMTTPMAOA | |
| SCHEMBL3647137 | 0.78 | PDPK1 (0.51) | PDPK1ACHEKDM1AMAOAMAOB | |
| SCHEMBL3637423 | 0.76 | PDPK1 (0.51) | PDPK1ACHEKDM1AMAOAMAOB | |
| SCHEMBL3642763 | 0.74 | PDPK1 (0.49) | PDPK1ACHEKDM1AMAOAMAOB | |
| SCHEMBL3643863 | 0.73 | ACHE (0.41) | ACHEMAOAMAOB | |
| SCHEMBL3645817 | 0.73 | ADRA2A (0.42) | — | |
| SCHEMBL3644335 | 0.71 | PDPK1 (0.46) | PDPK1ACHE | |
| SCHEMBL3646416 | 0.71 | PDPK1 (0.46) | PDPK1ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8232307-B2 | Indane-amine derivatives, their preparation and use as medicaments | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2012-07-31 | — | — | US | disclosed |
| US-20110053980-A1 | INDANE-AMINE DERIVATIVES, THEIR PREPARATION AND USE AS MEDICAMENTS | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2011-03-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110053980-A1 | INDANE-AMINE DERIVATIVES, THEIR PREPARATION AND USE AS MEDICAMENTS | INMT, IDO1, PNMT | PDPK1 3083/4885WDR5 3666/4885ACHE 60/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.