Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ALPL | P05186 | 1/20 | 0.40 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12605215 | 0.94 | SIGMAR1 (0.49) | SIGMAR1ALDH1A1SMN1; SMN2KDM4EALOX15 | |
| SCHEMBL27259214 | 0.85 | SIGMAR1 (0.56) | SIGMAR1ALDH1A1SMN1; SMN2KDM4EALOX15 | |
| SCHEMBL28679451 | 0.84 | ALDH1A1 (0.49) | SIGMAR1ALDH1A1SMN1; SMN2KDM4EALOX15 | |
| SCHEMBL23768343 | 0.84 | ALDH1A1 (0.53) | SIGMAR1ALDH1A1SMN1; SMN2KDM4ETDP1 | |
| SCHEMBL9098499 | 0.84 | ALDH1A1 (0.53) | SIGMAR1ALDH1A1SMN1; SMN2KDM4ETDP1 | |
| SCHEMBL4578879 | 0.84 | SIGMAR1 (0.55) | SIGMAR1ALDH1A1SMN1; SMN2KDM4EALOX15 | |
| SCHEMBL5095076 | 0.84 | SIGMAR1 (0.55) | SIGMAR1ALDH1A1SMN1; SMN2KDM4EALOX15 | |
| SCHEMBL8396113 | 0.84 | SIGMAR1 (0.55) | SIGMAR1ALDH1A1SMN1; SMN2KDM4EALOX15 | |
| SCHEMBL16731671 | 0.84 | ALDH1A1 (0.53) | SIGMAR1ALDH1A1SMN1; SMN2KDM4ETDP1 | |
| SCHEMBL12906765 | 0.81 | ALDH1A1 (0.53) | SIGMAR1ALDH1A1SMN1; SMN2KDM4EALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8492163-B2 | Methods, mixtures, kits and compositions pertaining to analyte determination | DH TECHNOLOGIES DEVELOPMENT PTE. LTD. (SG) | 2013-07-23 | — | — | US | disclosed |
| US-8492163-B2 | Methods, mixtures, kits and compositions pertaining to analyte determination | DH TECHNOLOGIES DEVELOPMENT PTE. LTD. (SG) | 2013-07-23 | — | — | US | disclosed |
| US-20120196378-A1 | Methods, Mixtures, Kits and Compositions Pertaining to Analyte Determination | DH TECHNOLOGIES DEVELOPMNET PTE LTD. (SI) | 2012-08-02 | — | — | US | disclosed |
| US-20120196378-A1 | Methods, Mixtures, Kits and Compositions Pertaining to Analyte Determination | DH TECHNOLOGIES DEVELOPMNET PTE LTD. (SI) | 2012-08-02 | — | — | US | disclosed |
| US-7906341-B2 | Isobaric sets, mass differential labeling sets; mass spectrometry | DH TECHNOLOGIES DEVELOPMENT PTE, LTD. (SG) | 2011-03-15 | — | — | US | disclosed |
| US-7906341-B2 | Isobaric sets, mass differential labeling sets; mass spectrometry | DH TECHNOLOGIES DEVELOPMENT PTE, LTD. (SG) | 2011-03-15 | — | — | US | disclosed |
| US-20080241955-A1 | Methods, Mixtures, Kits And Compositions Pertaining To Analyte Determination | APPLERA CORPORATION (US) | 2008-10-02 | — | — | US | disclosed |
| US-20080241955-A1 | Methods, Mixtures, Kits And Compositions Pertaining To Analyte Determination | APPLERA CORPORATION (US) | 2008-10-02 | — | — | US | disclosed |
| WO-2008005846-A2 | METHODS, MIXTURES, KITS AND COMPOSITIONS PERTAINING TO ANALYTE DETERMINATION | APPLERA CORPORATION (US) | 2008-01-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080241955-A1 | Methods, Mixtures, Kits And Compositions Pertaining To Analyte Determination | SRMS, KLK3, MPO | SIGMAR1 4448/4885ALDH1A1 130/4885SMN1; SMN2 2625/4885 |
| US-20120196378-A1 | Methods, Mixtures, Kits and Compositions Pertaining to Analyte Determination | SRMS, KLK3, MPO | SIGMAR1 4448/4885ALDH1A1 130/4885SMN1; SMN2 2625/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.