Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.46 |
| ▸ | MAPT | P10636 | 8/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 6/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.43 |
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | RECQL | P46063 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8511817 | 0.90 | ALDH1A1 (0.41) | ALDH1A1MAPTCYP1A2CYP3A4CYP2C19 | |
| SCHEMBL11300123 | 0.90 | ALDH1A1 (0.51) | ALDH1A1MAPTCYP1A2CYP3A4CYP2C19 | |
| SCHEMBL11300120 | 0.90 | ALDH1A1 (0.51) | ALDH1A1MAPTCYP1A2CYP3A4CYP2C19 | |
| SCHEMBL11956135 | 0.90 | ALDH1A1 (0.51) | ALDH1A1MAPTCYP1A2CYP3A4CYP2C19 | |
| SCHEMBL11891018 | 0.86 | ALDH1A1 (0.48) | ALDH1A1MAPTCYP1A2CYP3A4CYP2C19 | |
| SCHEMBL17976600 | 0.86 | ALDH1A1 (0.50) | ALDH1A1MAPTCYP1A2CYP3A4CYP2C19 | |
| SCHEMBL11302220 | 0.86 | ALDH1A1 (0.50) | ALDH1A1MAPTCYP1A2CYP3A4CYP2C19 | |
| SCHEMBL11302224 | 0.86 | ALDH1A1 (0.50) | ALDH1A1MAPTCYP1A2CYP3A4CYP2C19 | |
| SCHEMBL20565781 | 0.81 | HPGD (0.51) | ALDH1A1MAPTCYP1A2CYP3A4CYP2C19 | |
| SCHEMBL18797553 | 0.81 | HPGD (0.51) | ALDH1A1MAPTCYP1A2CYP3A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230127147-A1 | CONTINUOUS-FLOW PREPARATION METHOD OF DIOL SULFONE | UNIV FUDAN (CN) | 2023-04-27 | — | — | US | disclosed |
| EP-2665722-B1 | PROCESS FOR THE PREPARATION OF DIOL SULFONES | DSM SINOCHEM PHARM NL BV (NL) | 2016-08-17 | — | — | EP | disclosed |
| EP-2665722-B1 | PROCESS FOR THE PREPARATION OF DIOL SULFONES | DSM SINOCHEM PHARM NL BV (NL) | 2016-08-17 | — | — | EP | disclosed |
| US-9150562-B2 | Process for the preparation of diol sulfones | DSM SINOCHEM PHARMACEUTICALS NETHERLANDS B.V. (NL) | 2015-10-06 | — | — | US | disclosed |
| US-9150562-B2 | Process for the preparation of diol sulfones | DSM SINOCHEM PHARMACEUTICALS NETHERLANDS B.V. (NL) | 2015-10-06 | — | — | US | disclosed |
| US-9150562-B2 | Process for the preparation of diol sulfones | DSM SINOCHEM PHARMACEUTICALS NETHERLANDS B.V. (NL) | 2015-10-06 | — | — | US | disclosed |
| US-20130303779-A1 | PROCESS FOR THE PREPARATION OF DIOL SULFONES | DSM SINOCHEM PHARMACEUTICALS NETHERLANDS B.V. (NL) | 2013-11-14 | — | — | US | disclosed |
| US-20130303779-A1 | PROCESS FOR THE PREPARATION OF DIOL SULFONES | DSM SINOCHEM PHARMACEUTICALS NETHERLANDS B.V. (NL) | 2013-11-14 | — | — | US | disclosed |
| US-20130303779-A1 | PROCESS FOR THE PREPARATION OF DIOL SULFONES | DSM SINOCHEM PHARMACEUTICALS NETHERLANDS B.V. (NL) | 2013-11-14 | — | — | US | disclosed |
| WO-2012098048-A1 | PROCESS FOR THE PREPARATION OF DIOL SULFONES | DSM SINOCHEM PHARMACEUTICALS NETHERLANDS B.V. (NL) | 2012-07-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130303779-A1 | PROCESS FOR THE PREPARATION OF DIOL SULFONES | STS, DHCR7, TST | ALDH1A1 927/4885MAPT 3293/4885CYP1A2 85/4885 |
| US-20230127147-A1 | CONTINUOUS-FLOW PREPARATION METHOD OF DIOL SULFONE | DUOX2, SULT2A1, SQOR | ALDH1A1 2157/4885MAPT 3483/4885CYP1A2 304/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.