SCHEMBL119559

SCHEMBL119559

CC(=O)CC(=O)OC1CC(C)CCC1C(C)C

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 2/20 0.57
EPHX1 P07099 3/20 0.57
ALDH1A1 P00352 8/20 0.51
TSHR P16473 2/20 0.50
MAPT P10636 2/20 0.50
LMNA P02545 2/20 0.50
NPSR1 Q6W5P4 2/20 0.50
USP2 O75604 1/20 0.50
MEN1 O00255 2/20 0.49
KMT2A Q03164 2/20 0.49
HPGD P15428 2/20 0.49
MAPK1 P28482 2/20 0.48
KDM4E B2RXH2 1/20 0.48
GAA P10253 1/20 0.48
NPC1 O15118 1/20 0.45
MITF O75030 1/20 0.45
TP53 P04637 1/20 0.45
HTT P42858 1/20 0.45
RAB9A P51151 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12994248 1.00 CYP19A1 (0.57) CYP19A1EPHX1ALDH1A1TSHRMAPT
SCHEMBL15914460 1.00 CYP19A1 (0.57) CYP19A1EPHX1ALDH1A1TSHRMAPT
SCHEMBL18832114 1.00 CYP19A1 (0.57) CYP19A1EPHX1ALDH1A1TSHRMAPT
SCHEMBL10064065 1.00 CYP19A1 (0.57) CYP19A1EPHX1ALDH1A1TSHRMAPT
SCHEMBL5010580 0.92 CYP19A1 (0.61) CYP19A1EPHX1ALDH1A1TSHRMAPT
SCHEMBL5010581 0.88 CYP19A1 (0.57) CYP19A1EPHX1ALDH1A1TSHRMAPT
SCHEMBL19900145 0.87 CYP19A1 (0.56) CYP19A1EPHX1ALDH1A1TSHRMAPT
SCHEMBL13953844 0.87 CYP19A1 (0.56) CYP19A1EPHX1ALDH1A1TSHRMAPT
SCHEMBL25982610 0.87 CYP19A1 (0.56) CYP19A1EPHX1ALDH1A1TSHRMAPT
SCHEMBL1248258 0.87 CYP19A1 (0.56) CYP19A1EPHX1ALDH1A1TSHRMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 698 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3817575-B1 SOLUBILISATION OF COOLING AGENTS OF LOW SOLUBILITY SYMRISE AG (DE) 2025-10-15 EP claimed
EP-3494104-B1 WARMING SENSATION COMPOUNDS TAKASAGO PERFUMERY CO LTD (JP) 2023-11-15 EP claimed
EP-4103287-A1 COMPOSITIONS COMPRISING (BIO)-ALKANEDIOLS AND COOLING AGENTS Symrise AG (DE) 2022-12-21 EP claimed
WO-2022122903-A1 COMPOSITIONS COMPRISING (BIO)-ALKANEDIOLS AND COOLING AGENTS SYMRISE AG (DE) 2022-06-16 WO claimed
WO-2022122134-A1 COMPOSITIONS WITH (BIO)-ALKANEDIOLS AND COOLING AGENTS SYMRISE AG (DE) 2022-06-16 WO claimed
EP-3996506-A1 FORMULATIONS FOR CONTROL AND REPELLENCY OF BITING ARTHROPODS Bedoukian Research, Inc. (US) 2022-05-18 EP claimed
EP-3996505-A1 SYNERGISTIC FORMULATIONS FOR CONTROL AND REPELLENCY OF BITING ARTHROPODS Bedoukian Research, Inc. (US) 2022-05-18 EP claimed
CN-109803948-B Warming sensation compound 高砂香料工业株式会社 2022-03-01 CN claimed
US-11059771-B2 Warming sensation compounds TAKASAGO INTERNATIONAL CORPORATION (JP) 2021-07-13 US claimed
US-11034644-B2 2021-06-15 US claimed
US-20100273887-A1 MIXTURES COMPRISING PELLITORIN AND USES THEREOF SYMRISE GMBH & CO. KG (DE) 2010-10-28 US claimed
US-20100272655-A1 Menthylcarboxamides and Their Use as Cooling Agents BARDSLEY KATHRYN ANNE 2010-10-28 US claimed
CN-101784261-A Mixtures comprising pellitorin and uses thereof SYMRISE GMBH & CO KG 2010-07-21 CN claimed
EP-2187871-A1 MIXTURES COMPRISING PELLITORIN AND USES THEREOF Symrise GmbH & Co. KG (DE) 2010-05-26 EP claimed
CN-100577166-C Pharmaceutical formulations with improved oral drug resistance PROCTER & GAMBLE 2010-01-06 CN claimed
WO-2009021558-A1 MIXTURES COMPRISING PELLITORIN AND USES THEREOF SYMRISE GMBH & CO. KG (DE) 2009-02-19 WO claimed
EP-1339408-B1 LIQUID DRUG FORMULATIONS HAVING IMPROVED ORAL TOLERABILITY PROCTER & GAMBLE (US) 2005-06-29 EP claimed
CN-1575175-A Pharmaceutical formulations with improved oral drug resistance PROCTER & GAMBLE (US) 2005-02-02 CN claimed
EP-1339408-A1 DRUG FORMULATION HAVING IMPROVED ORAL TOLERABILITY THE PROCTER & GAMBLE COMPANY (US) 2003-09-03 EP claimed
WO-2002045714-A1 DRUG FORMULATION HAVING IMPROVED ORAL TOLERABILITY THE PROCTER & GAMBLE COMPANY (US) 2002-06-13 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11059771-B2 Warming sensation compounds TRPA1, TRPV1, TRPV4 CYP19A1 949/4885EPHX1 1930/4885ALDH1A1 1286/4885
US-11034644-B2 TRPA1, TRPV1, TRPV5 CYP19A1 759/4885EPHX1 1372/4885ALDH1A1 593/4885
US-20100272655-A1 Menthylcarboxamides and Their Use as Cooling Agents GMDS, CHIA, RIMKLA CYP19A1 1635/4885EPHX1 1156/4885ALDH1A1 1671/4885
US-20100273887-A1 MIXTURES COMPRISING PELLITORIN AND USES THEREOF NISCH, TAS2R40, TAS2R60 CYP19A1 1917/4885EPHX1 3306/4885ALDH1A1 3698/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.