Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 5/20 | 0.36 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.33 |
| ▸ | CD38 | P28907 | 1/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
| ▸ | MPO | P05164 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | CFD | P00746 | 1/20 | 0.31 |
| ▸ | KDM1A | O60341 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | MDM4 | O15151 | 1/20 | 0.30 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11956951 | 0.87 | METTL3 (0.34) | SLC22A12METTL3PKMPCSK9P2RX7 | |
| SCHEMBL13862214 | 0.87 | ALDH1A1 (0.37) | METTL3PCSK9MPOCFD | |
| SCHEMBL1046140 | 0.87 | METTL3 (0.44) | METTL3THRBCFDMAPT | |
| SCHEMBL11956461 | 0.87 | METTL3 (0.34) | SLC22A12METTL3PKMPCSK9P2RX7 | |
| SCHEMBL3246472 | 0.84 | METTL3 (0.39) | SLC22A12METTL3CFDMAPT | |
| SCHEMBL11956884 | 0.82 | MAPT (0.37) | SLC22A12PKMP2RX7MAPT | |
| SCHEMBL11956919 | 0.79 | METTL3 (0.43) | SLC22A12METTL3PKMPCSK9P2RX7 | |
| SCHEMBL1042873 | 0.78 | METTL3 (0.45) | METTL3CFDMAPT | |
| SCHEMBL3245181 | 0.76 | METTL3 (0.40) | SLC22A12METTL3PCSK9P2RX7CFD | |
| SCHEMBL11956950 | 0.76 | ALDH1A1 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8232401-B2 | Useful as an anti-HIV agent that particularly shows an anti-HIV action based on an integrase inhibitory activity; for treatment or prophylaxis of AIDS; for example, 6-(2,3-dichlorobenzyl)-1-(2-hydroxyethyl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid | JAPAN TOBACCO INC. (JP) | 2012-07-31 | — | — | US | disclosed |