SCHEMBL11957421

SCHEMBL11957421

CC(C)(C)[Si](Oc1ccc(CN)cc1)(c1ccccc1)c1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
MAOB P27338 12/20 0.47
LOXL2 Q9Y4K0 2/20 0.41
TAAR1 Q96RJ0 1/20 0.40
ST14 Q9Y5Y6 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.36
KEAP1 Q14145 1/20 0.36
NFE2L2 Q16236 1/20 0.36
LOX P28300 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25255096 0.88 TAAR1 (0.46) MAOBLOXL2TAAR1SMN1; SMN2
SCHEMBL754087 0.84 TRPA1 (0.41) MAOBSMN1; SMN2
SCHEMBL3540870 0.84 LTA4H (0.49)
SCHEMBL20954586 0.83 BCHE (0.46) SMN1; SMN2
SCHEMBL704145 0.82 CA4 (0.37) SMN1; SMN2
SCHEMBL7424773 0.81 MAOA (0.44) MAOBTAAR1SMN1; SMN2
SCHEMBL27600931 0.80 CA4 (0.46)
SCHEMBL7095572 0.79 MAOB (0.50) MAOBSMN1; SMN2
SCHEMBL29223363 0.79 HIF1A (0.46) MAOB
SCHEMBL7096596 0.78 ESR2 (0.46)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109415468-B Electro-optical polymers 国立研究开发法人情报通信研究机构 2024-06-07 CN disclosed
US-20120196989-A1 SYNTHESIS OF HOMOPOLYMERS AND BLOCK COPOLYMERS INTEZYNE TECHNOLOGIES, INCORPORATED (US) 2012-08-02 US disclosed
US-20110124840-A1 Synthesis of Homopolymers and Block Copolymers INTEZYNE TECHNOLOGIES, INC. 2011-05-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110124840-A1 Synthesis of Homopolymers and Block Copolymers PARG, PCNA, PARN MAOB 728/4885LOXL2 2748/4885TAAR1 3875/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.