Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | LTA4H | P09960 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3540870 | 0.84 | LTA4H (0.49) | TSHRLTA4H | |
| SCHEMBL11957421 | 0.84 | MAOB (0.47) | SMN1; SMN2MAOB | |
| SCHEMBL20954586 | 0.83 | BCHE (0.46) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL704145 | 0.82 | CA4 (0.37) | ALDH1A1TSHRLTA4HSMN1; SMN2 | |
| SCHEMBL6058734 | 0.81 | ALDH1A1 (0.37) | ALDH1A1TSHR | |
| SCHEMBL25255096 | 0.81 | TAAR1 (0.46) | SMN1; SMN2MAOB | |
| SCHEMBL3682169 | 0.81 | PPARG (0.39) | LTA4HSMN1; SMN2 | |
| SCHEMBL27600931 | 0.80 | CA4 (0.46) | TRPA1ALDH1A1CES2CES1LTA4H | |
| SCHEMBL7095572 | 0.79 | MAOB (0.50) | SMN1; SMN2MAOB | |
| SCHEMBL863227 | 0.79 | GSK3B (0.51) | SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114835742-B | Fluorescent probe for detecting fluoride ions and preparation method and application thereof | 上海应用技术大学 | 2024-01-23 | — | — | CN | claimed |
| CN-111518128-B | Fluorescent probe for detecting fluorine ions and preparation method and application thereof | 上海应用技术大学 | 2022-08-23 | — | — | CN | claimed |
| CN-115260165-B | Benzo nitrogen-containing five-membered heterocyclic compound and synthesis and application thereof | 中国科学院上海药物研究所 | 2024-08-06 | — | — | CN | disclosed |
| CN-114835742-B | Fluorescent probe for detecting fluoride ions and preparation method and application thereof | 上海应用技术大学 | 2024-01-23 | — | — | CN | disclosed |
| CN-115260165-A | Benzo nitrogen-containing five-membered heterocyclic compound and synthesis and application thereof | 中国科学院上海药物研究所 | 2022-11-01 | — | — | CN | disclosed |
| CN-111518128-B | Fluorescent probe for detecting fluorine ions and preparation method and application thereof | 上海应用技术大学 | 2022-08-23 | — | — | CN | disclosed |
| CN-111518128-A | Fluorescent probe for detecting fluorine ions and preparation method and application thereof | 上海应用技术大学 | 2020-08-11 | — | — | CN | disclosed |
| EP-2430004-B1 | NOVEL OXAZOLIDINONE DERIVATIVES AND THEIR USE AS OREXIN RECEPTOR ANTAGONISTS | ACTELION PHARMACEUTICALS LTD (CH) | 2013-07-17 | — | — | EP | disclosed |
| US-8329686-B2 | Isatin analogues and uses therefor | WASHINGTON UNIVERSITY (US) | 2012-12-11 | — | — | US | disclosed |
| US-8329706-B2 | Oxazolidinone derivatives | ACTELION PHARMACEUTICALS LTD. (CH) | 2012-12-11 | — | — | US | disclosed |
| US-20120101111-A1 | NOVEL OXAZOLIDINONE DERIVIATIVES | IDORSIA PHARMACEUTICALS LTD (CH) | 2012-04-26 | — | — | US | disclosed |
| EP-2430004-A2 | NOVEL OXAZOLIDINONE DERIVATIVES AND THEIR USE AS OREXIN RECEPTOR ANTAGONISTS | Actelion Pharmaceuticals Ltd. (CH) | 2012-03-21 | — | — | EP | disclosed |
| WO-2010131192-A2 | NOVEL OXAZOLIDINONE DERIVATIVES | ACTELION PHARMACEUTICALS LTD (CH) | 2010-11-18 | — | — | WO | disclosed |
| US-7705188-B2 | Structural modification of resveratrol: sodium resverastatin phosphate | Arizona Board of Regents, a body corporate of the State of Arizona, Acting for and on Behalf of the Arizona State University (US) | 2010-04-27 | — | — | US | disclosed |
| US-20090068105-A1 | ISATIN ANALOGUES AND USES THEREFOR | WASHINGTON UNIVERSITY IN ST. LOUIS | 2009-03-12 | — | — | US | disclosed |
| US-20050240062-A1 | Structural modification of resveratrol: Sodium resverastatin phosphate | NATIONAL INSTITUTES OF HEALTH | 2005-10-27 | — | — | US | disclosed |
| WO-2003086414-A1 | STRUCTURAL MODIFICATION OF RESVERATROL: SODIUM RESVERASTATIN PHOSPHATE | ARIZONA BOARD OF REGENTS (US) | 2003-10-23 | — | — | WO | disclosed |
| WO-1995031461-A1 | PREPARATION OF 2-ARYL CARBAPENEMS | MERCK & CO., INC. (US) | 1995-11-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120101111-A1 | NOVEL OXAZOLIDINONE DERIVIATIVES | HCRTR2, HCRTR1, NPY4R | TRPA1 646/4885ALDH1A1 715/4885TSHR 135/4885 |
| US-20050240062-A1 | Structural modification of resveratrol: Sodium resverastatin phosphate | PI4KB, HDAC4, PIK3CA | TRPA1 4279/4885ALDH1A1 3559/4885TSHR 4086/4885 |
| US-20090068105-A1 | ISATIN ANALOGUES AND USES THEREFOR | CASP7, CASP3, HASPIN | TRPA1 3986/4885ALDH1A1 2911/4885TSHR 4234/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.