SCHEMBL1196089

SCHEMBL1196089

Cc1c(N)ccc(C#N)c1C

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AR P10275 7/20 0.43
CYP3A4 P08684 4/20 0.40
TSHR P16473 3/20 0.40
PIK3CA P42336 1/20 0.40
ALDH1A1 P00352 3/20 0.39
KDM4E B2RXH2 2/20 0.39
USP2 O75604 1/20 0.39
MAPT P10636 2/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
MEN1 O00255 1/20 0.36
LMNA P02545 1/20 0.36
GAA P10253 1/20 0.36
HPGD P15428 1/20 0.36
HTT P42858 1/20 0.36
KMT2A Q03164 1/20 0.36
CYP1A2 P05177 2/20 0.35
CYP2C9 P11712 1/20 0.35
CYP2C19 P33261 1/20 0.35
GRM6 O15303 1/20 0.35
MAPK1 P28482 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1585098 0.84 AR (0.52) ARTSHRALDH1A1KDM4EUSP2
SCHEMBL15365364 0.84 KDM4E (0.38) ARCYP3A4TSHRPIK3CAALDH1A1
SCHEMBL2428317 0.82 GRM6 (0.41) ARCYP3A4TSHRPIK3CAALDH1A1
SCHEMBL9575173 0.82 GRM6 (0.41) ARCYP3A4TSHRPIK3CAALDH1A1
SCHEMBL973688 0.80 AR (0.49) ARALDH1A1KDM4EUSP2
SCHEMBL152108 0.80 EGLN2 (0.43) ARCYP3A4TSHRPIK3CAALDH1A1
SCHEMBL18299825 0.80 ALDH1A1 (0.36) ARCYP3A4TSHRPIK3CAALDH1A1
SCHEMBL2956480 0.80 ALDH1A1 (0.36) ARCYP3A4TSHRPIK3CAALDH1A1
SCHEMBL29533592 0.80 AR (0.40) ARTSHRALDH1A1KDM4EUSP2
SCHEMBL27709086 0.80 AR (0.40) ARCYP3A4TSHRALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0255956-A2 P-Type liquid crystal composition Sato, Hisato (JP) 1988-02-17 EP claimed
JP-63041589-A None JP disclosed
US-20250171417-A1 HETEROCYCLIC DERIVATIVE, AND COMPOSITION AND PHARMACEUTICAL USE THEREOF XIZANG HAISCO PHARMACEUTICAL CO., LTD. (CN) 2025-05-29 US disclosed
CN-118475567-A Heterocyclic derivative, composition and pharmaceutical application thereof 西藏海思科制药有限公司 2024-08-09 CN disclosed
EP-4385985-A1 HETEROCYCLIC DERIVATIVE, AND COMPOSITION AND PHARMACEUTICAL USE THEREOF Xizang Haisco Pharmaceutical Co., Ltd. (CN) 2024-06-19 EP disclosed
CN-116724067-A Silicone urethane (meth) acrylates and their use in 3D printing resins and coating compositions 赢创运营有限公司 2023-09-08 CN disclosed
CN-116583546-A Matrix resin for producing fiber composite materials 赢创运营有限公司 2023-08-11 CN disclosed
US-11648234-B2 Selective androgen receptor degrader (SARD) ligands and methods of use UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) 2023-05-16 US disclosed
WO-2023016518-A1 HETEROCYCLIC DERIVATIVE, AND COMPOSITION AND PHARMACEUTICAL USE THEREOF 四川海思科制药有限公司 2023-02-16 WO disclosed
WO-2023016518-A1 HETEROCYCLIC DERIVATIVE, AND COMPOSITION AND PHARMACEUTICAL USE THEREOF 四川海思科制药有限公司 2023-02-16 WO disclosed
US-7199147-B2 Rho kinase inhibitors DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) 2007-04-03 US disclosed
US-20040138286-A1 Rho kinase inhibitors DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) 2004-07-15 US disclosed
EP-1403255-A1 Rho KINASE INHIBITORS SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) 2004-03-31 EP disclosed
CN-1284063-A Compounds ASTRA ZENECA LTD (SE) 2001-02-14 CN disclosed
US-5061605-A IMPROVED SENSITIVITY TO LONG WAVELENGTHS FUJI PHOTO FILM CO., LTD. (JP) 1991-10-29 US disclosed
EP-0255956-A3 P-TYPE LIQUID CRYSTAL COMPOSITION Sato, Hisato (JP) 1989-06-07 EP disclosed
JP-S6341589-A P-TYPE LIQUID CRYSTAL COMPOSITION SATO HISATO 1988-02-22 JP disclosed
EP-0255956-A2 P-Type liquid crystal composition Sato, Hisato (JP) 1988-02-17 EP disclosed
EP-0255956-A2 P-Type liquid crystal composition Sato, Hisato (JP) 1988-02-17 EP disclosed
US-4636459-A PHOTOINITIATOR AND UNSATURATED MONOMER; PRINTING PLATES FUJI PHOTO FILM CO., LTD. (JP) 1987-01-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11648234-B2 Selective androgen receptor degrader (SARD) ligands and methods of use AR, BRCA1, FSHR AR 1/4885CYP3A4 2397/4885TSHR 838/4885
US-20040138286-A1 Rho kinase inhibitors ROCK1, ROCK2, ARHGDIA AR 3751/4885CYP3A4 3113/4885TSHR 2487/4885
US-20250171417-A1 HETEROCYCLIC DERIVATIVE, AND COMPOSITION AND PHARMACEUTICAL USE THEREOF AR, BCKDK, CYP11B2 AR 1/4885CYP3A4 144/4885TSHR 3687/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.