SCHEMBL11962349

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL9927158	1.00	ALDH1A1 (0.52)	ALDH1A1HSD17B10HPGDCYP1A2THRB
	SCHEMBL9927159	0.91	ALDH1A1 (0.50)	ALDH1A1HSD17B10HPGDCYP1A2THRB
	SCHEMBL9927191	0.90	CYP1A2 (0.46)	ALDH1A1HSD17B10HPGDCYP1A2THRB
	SCHEMBL11990961	0.85	CYP1A2 (0.43)	ALDH1A1HSD17B10HPGDCYP1A2THRB
	SCHEMBL9927309	0.85	CYP1A2 (0.43)	ALDH1A1HSD17B10HPGDCYP1A2THRB
	SCHEMBL14339297	0.85	KDM4E (0.50)	ALDH1A1HSD17B10HPGDCYP1A2KDM4E
	SCHEMBL14339282	0.85	KDM4E (0.50)	ALDH1A1HSD17B10HPGDCYP1A2KDM4E
	SCHEMBL1244976	0.84	KDM4E (0.53)	ALDH1A1HSD17B10HPGDCYP1A2KDM4E
	SCHEMBL29380351	0.84	KDM4E (0.53)	ALDH1A1HSD17B10HPGDCYP1A2KDM4E
	SCHEMBL9927325	0.83	CYP1A2 (0.59)	ALDH1A1HSD17B10HPGDCYP1A2THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.