Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.35 |
| ▸ | RAB9A | P51151 | 6/20 | 0.35 |
| ▸ | NPC1 | O15118 | 4/20 | 0.35 |
| ▸ | TP53 | P04637 | 3/20 | 0.35 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.35 |
| ▸ | GRK6 | P43250 | 1/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | AHR | P35869 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.32 |
| ▸ | CASP3 | P42574 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.32 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11963087 | 0.89 | KMT2A (0.34) | MEN1KMT2ARAB9ANPC1TP53 | |
| Deferitrin SCHEMBL1272026 | 0.87 | TYR (0.35) | MAPTHPGD | |
| SCHEMBL6314483 | 0.85 | KDM4E (0.40) | MAPTL3MBTL1HPGD | |
| SCHEMBL6314485 | 0.85 | KDM4E (0.40) | MAPTL3MBTL1HPGD | |
| SCHEMBL20175941 | 0.83 | ALDH1A1 (0.35) | MEN1KMT2ARAB9ANPC1TP53 | |
| SCHEMBL1534233 | 0.83 | HTR2B (0.44) | RAB9ANPC1TP53MAPTTDP1 | |
| SCHEMBL3301483 | 0.83 | NPC1 (0.40) | MEN1KMT2ARAB9ANPC1GRK6 | |
| SCHEMBL3301476 | 0.83 | NPC1 (0.40) | MEN1KMT2ARAB9ANPC1GRK6 | |
| SCHEMBL13318367 | 0.83 | ACMSD (0.32) | MEN1KMT2AMAPTALOX15TDP1 | |
| SCHEMBL10331305 | 0.83 | ACMSD (0.32) | MEN1KMT2AMAPTALOX15TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8846731-B2 | Salts and polymorphs of desazadesferrithiocin polyether analogues as metal chelation agents | FERROKIN BIOSCIENCES, INC. (US) | 2014-09-30 | — | — | US | disclosed |
| US-8829197-B2 | Salts and polymorphs of desazadesferrithiocin polyether analogues as metal chelation agents | FERROKIN BIOSCIENCES, INC. (US) | 2014-09-09 | — | — | US | disclosed |
| US-20120270911-A1 | NOVEL SALTS AND POLYMORPHS OF DESAZADESFERRITHIOCIN POLYETHER ANALOGUES AS METAL CHELATION AGENTS | FERROKIN BIOSCIENCES, INC. (US) | 2012-10-25 | — | — | US | disclosed |
| US-20120202857-A1 | NOVEL SALTS AND POLYMORPHS OF DESAZADESFERRITHIOCIN POLYETHER ANALOGUES AS METAL CHELATION AGENTS | FERROKIN BIOSCIENCES, INC. (US) | 2012-08-09 | — | — | US | disclosed |
| US-8063227-B2 | Salts and polymorphs of desazadesferrithiocin polyether analogues as metal chelation agents | FERROKIN BIOSCIENCES, INC. (US) | 2011-11-22 | — | — | US | disclosed |
| US-20110160257-A1 | NOVEL SALTS AND POLYMORPHS OF DESAZADESFERROTHIOCIN POLYETHER ANALOGUES AS METAL CHELATION AGENTS | FERROKIN BIOSCIENCES, INC. (US) | 2011-06-30 | — | — | US | disclosed |
| US-20100137383-A1 | NOVEL SALTS AND POLYMORPHS OF DESAZADESFERROTHIOCIN POLYETHER ANALOGUES AS METAL CHELATION AGENTS | FERROKIN BIOSCIENCES, INC. (US) | 2010-06-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110160257-A1 | NOVEL SALTS AND POLYMORPHS OF DESAZADESFERROTHIOCIN POLYETHER ANALOGUES AS METAL CHELATION AGENTS | SLC39A14, SLC40A1, SLC39A11 | MEN1 1802/4885KMT2A 3963/4885RAB9A 1109/4885 |
| US-20120202857-A1 | NOVEL SALTS AND POLYMORPHS OF DESAZADESFERRITHIOCIN POLYETHER ANALOGUES AS METAL CHELATION AGENTS | SLC39A14, SLC40A1, SLC39A11 | MEN1 1725/4885KMT2A 3881/4885RAB9A 1221/4885 |
| US-20120270911-A1 | NOVEL SALTS AND POLYMORPHS OF DESAZADESFERRITHIOCIN POLYETHER ANALOGUES AS METAL CHELATION AGENTS | SLC39A14, SLC40A1, SLC39A11 | MEN1 1725/4885KMT2A 3881/4885RAB9A 1221/4885 |
| US-20100137383-A1 | NOVEL SALTS AND POLYMORPHS OF DESAZADESFERROTHIOCIN POLYETHER ANALOGUES AS METAL CHELATION AGENTS | SLC39A14, SLC40A1, SLC39A11 | MEN1 1802/4885KMT2A 3963/4885RAB9A 1109/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.