Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.32 |
| ▸ | TTR | P02766 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 4/20 | 0.32 |
| ▸ | RXRA | P19793 | 1/20 | 0.32 |
| ▸ | RXRB | P28702 | 1/20 | 0.32 |
| ▸ | RXRG | P48443 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.31 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | FYN | P06241 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10331305 | 1.00 | ACMSD (0.32) | ACMSDTTRCNR2RXRARXRB | |
| SCHEMBL13408606 | 0.91 | ACMSD (0.34) | ACMSDCNR2RXRARXRBRXRG | |
| Deferitrin SCHEMBL1272026 | 0.84 | TYR (0.35) | KDM4EALDH1A1POLBGAAMAPT | |
| SCHEMBL11963155 | 0.83 | MEN1 (0.35) | MEN1EGFRMAPTHPGDALOX15 | |
| SCHEMBL6314483 | 0.82 | KDM4E (0.40) | TTRRXRARXRBRXRGKDM4E | |
| SCHEMBL6314485 | 0.82 | KDM4E (0.40) | TTRRXRARXRBRXRGKDM4E | |
| SCHEMBL1534233 | 0.80 | HTR2B (0.44) | KDM4EALDH1A1MAPTHPGDHSD17B10 | |
| SCHEMBL3301483 | 0.80 | NPC1 (0.40) | KDM4EMEN1ALDH1A1CYP1A2POLB | |
| SCHEMBL3301476 | 0.80 | NPC1 (0.40) | KDM4EMEN1ALDH1A1CYP1A2POLB | |
| SCHEMBL20175902 | 0.79 | CNR1 (0.41) | CNR2KDM4EMEN1USP2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100137346-A1 | DESFERRITHIOCIN ANALOGUE ACTINIDE DECORPORATION AGENTS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2010-06-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100137346-A1 | DESFERRITHIOCIN ANALOGUE ACTINIDE DECORPORATION AGENTS | TFRC, SLC40A1, FIBP | ACMSD 2932/4885TTR 210/4885CNR2 4469/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.