Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | AR | P10275 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | PLG | P00747 | 1/20 | 0.40 |
| ▸ | PLAU | P00749 | 1/20 | 0.40 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.40 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | STS | P08842 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2233407 | 0.78 | TDP1 (0.54) | KMT2AHTTMAOBF2PLG | |
| SCHEMBL7837193 | 0.75 | MAOB (0.75) | MAPTMAOBARSLC6A2SLC6A4 | |
| SCHEMBL1195899 | 0.75 | HSD11B1 (0.45) | SLC6A2SLC6A4SLC6A3F2PLG | |
| SCHEMBL1195227 | 0.74 | ALPL (0.48) | SLC6A2SLC6A4SLC6A3CA1CA2 | |
| Phenyl Phenylmethanesulfonate SCHEMBL6912876 | 0.73 | KMT2A (1.00) | KMT2AHTTARF2PRSS1 | |
| SCHEMBL6812108 | 0.72 | SLC6A2 (0.44) | SLC6A2SLC6A4SLC6A3F2PLG | |
| SCHEMBL6100031 | 0.72 | MAOB (0.71) | MAPTMAOBARSLC6A2SLC6A4 | |
| Phenyl Phenylmethanesulfonate SCHEMBL27917341 | 0.71 | KMT2A (0.96) | KMT2AHTTARF2PRSS1 | |
| SCHEMBL1196441 | 0.71 | MEN1 (0.62) | KMT2AHTTARCA1CA2 | |
| SCHEMBL11496986 | 0.71 | KMT2A (0.50) | KMT2AHTTARPRSS1PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110040115-A1 | INTERMEDIATES AND PROCESS FOR THE PREPARATION OF AROMATIC DERIVATIVES OF 1-ADAMANTANE | FINORGA SAS (FR) | 2011-02-17 | — | — | US | disclosed |
| EP-1986985-B1 | INTERMEDIATES AND PROCESS FOR THE PREPARATION OF AROMATIC DERIVATIVES OF 1-ADAMANTANE | FINORGA SAS (FR) | 2010-09-01 | — | — | EP | disclosed |
| EP-1986985-A1 | INTERMEDIATES AND PROCESS FOR THE PREPARATION OF AROMATIC DERIVATIVES OF 1-ADAMANTANE | FINORGA SAS (FR) | 2008-11-05 | — | — | EP | disclosed |
| WO-2007063523-A1 | INTERMEDIATES AND PROCESS FOR THE PREPARATION OF AROMATIC DERIVATIVES OF 1-ADAMANTANE | FINORGA SAS (FR) | 2007-06-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110040115-A1 | INTERMEDIATES AND PROCESS FOR THE PREPARATION OF AROMATIC DERIVATIVES OF 1-ADAMANTANE | DHPS, APOBEC3A, DDC | KMT2A 4560/4885HTT 1269/4885MAPT 2325/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.