Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 2/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.36 |
| ▸ | TACR1 | P25103 | 2/20 | 0.35 |
| ▸ | CASR | P41180 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | F7 | P08709 | 1/20 | 0.34 |
| ▸ | F3 | P13726 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | COMT | P21964 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11965001 | 0.89 | LMNA (0.41) | PTGS2BRD4TACR1KDM4EMAPT | |
| SCHEMBL12603542 | 0.86 | MAPT (0.36) | PTGS2ALDH1A1ADORA2BTACR1KDM4E | |
| SCHEMBL12603541 | 0.86 | TACR1 (0.37) | PTGS2ALDH1A1BRD4TACR1KDM4E | |
| SCHEMBL11910054 | 0.81 | F7 (0.44) | PTGS2BRD4TACR1KDM4EMAPT | |
| SCHEMBL23403210 | 0.80 | ESR1 (0.40) | PTGS2ESR1POLBALDH1A1MAPT | |
| SCHEMBL11965006 | 0.78 | PTGS2 (0.40) | PTGS2ESR1POLBALDH1A1BRD4 | |
| SCHEMBL11965009 | 0.76 | HEXA (0.40) | PTGS2ESR1ALDH1A1BRD4ADORA2B | |
| SCHEMBL23402792 | 0.76 | TLR8 (0.38) | PTGS2ESR1POLBALDH1A1BRD4 | |
| SCHEMBL11965017 | 0.75 | PTGS2 (0.38) | PTGS2ESR1ALDH1A1BRD4ADORA2B | |
| SCHEMBL11965014 | 0.75 | PTGS2 (0.38) | PTGS2ESR1ALDH1A1BRD4ADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8242055-B2 | Herbicidally and insecticidally active phenyl-substituted pyridazinones | BAYER CROPSCIENCE AG (DE) | 2012-08-14 | — | — | US | disclosed |
| US-20110118118-A1 | HERBICIDALLY ACTIVE PHENYL-SUBSTITUTED PYRIDAZINONES | BAYER CROPSCIENCE AG (DE) | 2011-05-19 | — | — | US | disclosed |
| US-20100184602-A1 | HERBICIDALLY AND INSECTICIDALLY ACTIVE PHENYL-SUBSTITUTED PYRIDAZINONES | BAYER CROPSCIENCE AG (DE) | 2010-07-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100184602-A1 | HERBICIDALLY AND INSECTICIDALLY ACTIVE PHENYL-SUBSTITUTED PYRIDAZINONES | CYP4X1, PRDX1, PNPO | PTGS2 1062/4885ESR1 4353/4885POLB 1087/4885 |
| US-20110118118-A1 | HERBICIDALLY ACTIVE PHENYL-SUBSTITUTED PYRIDAZINONES | PNPO, PDXK, PRDX1 | PTGS2 1491/4885ESR1 3945/4885POLB 451/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.