Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HEXA | P06865 | 1/20 | 0.40 |
| ▸ | HEXB | P07686 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | CMA1 | P23946 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11965017 | 0.91 | PTGS2 (0.38) | HEXAHEXBPTGS2BRD4ESR1 | |
| SCHEMBL11965008 | 0.90 | MAPT (0.43) | HEXAHEXBALOX15BRD4RECQL | |
| SCHEMBL8901216 | 0.88 | CASR (0.44) | HEXAHEXBALOX15ALDH1A1KDM4E | |
| SCHEMBL12603547 | 0.88 | BRD4 (0.38) | HEXAHEXBALOX15BRD4CMA1 | |
| SCHEMBL12603548 | 0.87 | MAPT (0.36) | HEXAHEXBALOX15BRD4RECQL | |
| SCHEMBL11965006 | 0.87 | PTGS2 (0.40) | PTGS2BRD4ESR1ALDH1A1KDM4E | |
| SCHEMBL11965007 | 0.85 | HEXA (0.43) | HEXAHEXBALOX15BRD4ALDH1A1 | |
| SCHEMBL8902391 | 0.85 | ALDH1A1 (0.46) | HEXAHEXBALOX15ALDH1A1AKR1B1 | |
| SCHEMBL8901006 | 0.84 | TACR1 (0.42) | HEXAHEXBALOX15BRD4GAA | |
| SCHEMBL8901050 | 0.84 | ADRA1A (0.40) | BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8242055-B2 | Herbicidally and insecticidally active phenyl-substituted pyridazinones | BAYER CROPSCIENCE AG (DE) | 2012-08-14 | — | — | US | disclosed |
| US-20110118118-A1 | HERBICIDALLY ACTIVE PHENYL-SUBSTITUTED PYRIDAZINONES | BAYER CROPSCIENCE AG (DE) | 2011-05-19 | — | — | US | disclosed |
| US-20100184602-A1 | HERBICIDALLY AND INSECTICIDALLY ACTIVE PHENYL-SUBSTITUTED PYRIDAZINONES | BAYER CROPSCIENCE AG (DE) | 2010-07-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100184602-A1 | HERBICIDALLY AND INSECTICIDALLY ACTIVE PHENYL-SUBSTITUTED PYRIDAZINONES | CYP4X1, PRDX1, PNPO | HEXA 959/4885HEXB 483/4885ALOX15 485/4885 |
| US-20110118118-A1 | HERBICIDALLY ACTIVE PHENYL-SUBSTITUTED PYRIDAZINONES | PNPO, PDXK, PRDX1 | HEXA 677/4885HEXB 308/4885ALOX15 946/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.