Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.43 |
| ▸ | TP53 | P04637 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 7/20 | 0.39 |
| ▸ | NPC1 | O15118 | 6/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 6/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 5/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 5/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11965065 | 0.84 | CYP1A2 (0.52) | CYP1A2CYP2D6HSD17B10SMN1; SMN2TP53 | |
| SCHEMBL11965101 | 0.79 | CYP1A2 (0.79) | CYP1A2CYP2D6HSD17B10SMN1; SMN2TP53 | |
| SCHEMBL11902893 | 0.77 | SMN1; SMN2 (0.56) | CYP1A2CYP2D6HSD17B10SMN1; SMN2TP53 | |
| SCHEMBL21369979 | 0.72 | S1PR1 (0.54) | CYP3A4 | |
| SCHEMBL11965103 | 0.70 | CYP11B2 (0.38) | CYP19A1CYP11B1CYP11B2SRD5A1 | |
| SCHEMBL7665011 | 0.68 | PARP10 (0.46) | CYP2D6CYP19A1CYP11B1CYP11B2SRD5A1 | |
| SCHEMBL17264641 | 0.66 | MAPT (0.55) | CYP1A2CYP2D6HSD17B10SMN1; SMN2TP53 | |
| SCHEMBL5729648 | 0.64 | S1PR1 (0.60) | CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL1009901 | 0.64 | MAOA (0.50) | ALDH1A1CYP19A1CYP11B1CYP11B2MAPT | |
| SCHEMBL3369293 | 0.63 | CYP11B2 (0.46) | CYP19A1CYP11B1CYP11B2SRD5A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120202794-A1 | COMPOUNDS | PHARMASSET, INC. (US) | 2012-08-09 | — | — | US | disclosed |
| US-20120202794-A1 | COMPOUNDS | PHARMASSET, INC. (US) | 2012-08-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120202794-A1 | COMPOUNDS | HAVCR2, MAVS, GOT2 | CYP1A2 820/4885CYP2D6 1056/4885HSD17B10 651/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.