Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.79 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.79 |
| ▸ | MAPT | P10636 | 4/20 | 0.79 |
| ▸ | SLC25A20 | O43772 | 3/20 | 0.79 |
| ▸ | TP53 | P04637 | 3/20 | 0.79 |
| ▸ | TSHR | P16473 | 3/20 | 0.79 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.79 |
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.79 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.79 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.79 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.79 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.79 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.79 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.79 |
| ▸ | THPO | P40225 | 1/20 | 0.79 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.79 |
| ▸ | RECQL | P46063 | 1/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.59 |
| ▸ | GMNN | O75496 | 3/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28525260 | 1.00 | MEN1 (0.79) | MEN1KMT2AMAPTSLC25A20TP53 | |
| SCHEMBL997303 | 1.00 | MEN1 (0.79) | MEN1KMT2AMAPTSLC25A20TP53 | |
| SCHEMBL995307 | 1.00 | MEN1 (0.79) | MEN1KMT2AMAPTSLC25A20TP53 | |
| SCHEMBL15050371 | 1.00 | MEN1 (0.79) | MEN1KMT2AMAPTSLC25A20TP53 | |
| Hydrochloric Acid SCHEMBL28705824 | 0.99 | MEN1 (0.77) | MEN1KMT2AMAPTSLC25A20TP53 | |
| SCHEMBL14931520 | 0.98 | MEN1 (0.76) | MEN1KMT2AMAPTSLC25A20TP53 | |
| SCHEMBL787164 | 0.94 | MEN1 (0.74) | MEN1KMT2AMAPTSLC25A20TP53 | |
| SCHEMBL8593280 | 0.94 | MEN1 (0.74) | MEN1KMT2AMAPTSLC25A20TP53 | |
| SCHEMBL18075036 | 0.94 | MEN1 (0.88) | MEN1KMT2AMAPTSLC25A20TP53 | |
| SCHEMBL16344748 | 0.94 | MEN1 (0.88) | MEN1KMT2AMAPTSLC25A20TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109632924-B | Plasma lipid marker of human macular neovascular diseases and application thereof | 上海市第一人民医院 | 2022-02-08 | — | — | CN | claimed |
| US-12534439-B2 | Xanthohumol derivatives and methods for making and using | OREGON STATE UNIVERSITY (US) | 2026-01-27 | — | — | US | disclosed |
| CN-118604350-A | Biomarker for diagnosis of age-related macular degeneration, detection kit and application thereof | 上海市第一人民医院 | 2024-09-06 | — | — | CN | disclosed |
| US-20240142469-A1 | METABOLIC BIOMARKERS FOR ASSESSING HEART FAILURE IN A SINGLE VENTRICLE PEDIATRIC SUBJECT | THE TRUSTEES OF INDIANA UNIVERSITY | 2024-05-02 | — | — | US | disclosed |
| US-20240051922-A1 | XANTHOHUMOL DERIVATIVES AND METHODS FOR MAKING AND USING | OREGON STATE UNIVERSITY (US) | 2024-02-15 | — | — | US | disclosed |
| CN-109632924-B | Plasma lipid marker of human macular neovascular diseases and application thereof | 上海市第一人民医院 | 2022-02-08 | — | — | CN | disclosed |
| US-20120214870-A1 | METHODS FOR DIAGNOSIS AND TREATMENT OF CHRONIC FATIGUE SYNDROME | UNIVERSITY OF SOUTH AUSTRALIA (AU) | 2012-08-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12534439-B2 | Xanthohumol derivatives and methods for making and using | MT-CO1, MT-CO2, PC | MEN1 3741/4885KMT2A 3257/4885MAPT 3792/4885 |
| US-20240051922-A1 | XANTHOHUMOL DERIVATIVES AND METHODS FOR MAKING AND USING | XDH, PC, TFB2M | MEN1 4237/4885KMT2A 2952/4885MAPT 3357/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.