Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 10/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 10/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 9/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 9/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 9/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 9/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 9/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 9/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 9/20 | 0.38 |
| ▸ | HDAC9 | Q9UKV0 | 9/20 | 0.38 |
| ▸ | HDAC5 | Q9UQL6 | 9/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | FBP1 | P09467 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13130765 | 0.83 | ALOX15 (0.35) | HDAC1HDAC6HDAC3HDAC4HDAC7 | |
| SCHEMBL18649524 | 0.82 | EPHX1 (0.47) | EPHX1TDP1TSHRGAAMEN1 | |
| SCHEMBL464489 | 0.79 | EPHX1 (0.46) | EPHX1HDAC1HDAC6HDAC3HDAC4 | |
| SCHEMBL13341025 | 0.79 | POLB (0.38) | HDAC1HDAC6HDAC3HDAC4HDAC7 | |
| SCHEMBL15145438 | 0.79 | EPHX1 (0.44) | EPHX1HDAC1HDAC6HDAC3HDAC4 | |
| SCHEMBL14176517 | 0.77 | CA1 (0.31) | — | |
| SCHEMBL22546603 | 0.75 | GAA (0.33) | GAA | |
| SCHEMBL12248326 | 0.75 | POLB (0.35) | TSHRFBP1 | |
| SCHEMBL1082707 | 0.75 | TDP1 (0.56) | EPHX1TDP1TSHRGAAALDH1A1 | |
| SCHEMBL13139407 | 0.74 | MEN1 (0.42) | EPHX1MEN1KMT2AFBP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120213854-A1 | METHODS OF TREATING A SUBJECT AND RELATED PARTICLES, POLYMERS AND COMPOSITIONS | CERULEAN PHARMA INC. | 2012-08-23 | — | — | US | disclosed |
| US-20120202772-A1 | CYCLODEXTRIN-BASED POLYMERS FOR THERAPEUTIC DELIVERY | GLUCKSMANN ALEXANDRA (US) | 2012-08-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120202772-A1 | CYCLODEXTRIN-BASED POLYMERS FOR THERAPEUTIC DELIVERY | PSMG3, COPB1, PSMA6 | EPHX1 3709/4885HDAC1 720/4885HDAC6 126/4885 |
| US-20120213854-A1 | METHODS OF TREATING A SUBJECT AND RELATED PARTICLES, POLYMERS AND COMPOSITIONS | HLA-DRB1, TSG101, IAPP | EPHX1 2213/4885HDAC1 317/4885HDAC6 19/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.