Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | NAMPT | P43490 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 4/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.42 |
| ▸ | HTT | P42858 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.41 |
| ▸ | MGLL | Q99685 | 3/20 | 0.41 |
| ▸ | FAAH | O00519 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19703688 | 0.95 | PTGS1 (0.50) | MAPTNAMPTLMNAPKMGAA | |
| SCHEMBL17175252 | 0.93 | NAMPT (0.43) | MAPTNAMPTLMNAPKMHPGD | |
| SCHEMBL14868081 | 0.92 | NAMPT (0.44) | MAPTNAMPTLMNAPKMHPGD | |
| SCHEMBL17740044 | 0.92 | LMNA (0.52) | MAPTNAMPTLMNAPKMGAA | |
| SCHEMBL13327325 | 0.90 | MAPT (0.46) | MAPTNAMPTLMNAPKMGAA | |
| SCHEMBL21648875 | 0.89 | PTGS1 (0.45) | MAPTNAMPTLMNAPKMHPGD | |
| SCHEMBL19116815 | 0.89 | PTGS1 (0.49) | MAPTNAMPTLMNAPKMHPGD | |
| SCHEMBL12641968 | 0.89 | LMNA (0.43) | MAPTNAMPTLMNAPKMHPGD | |
| SCHEMBL21164830 | 0.88 | PTGS1 (0.39) | MAPTNAMPTLMNAPKMGAA | |
| SCHEMBL17453149 | 0.88 | PTGS1 (0.39) | MAPTNAMPTLMNAPKMGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240067650-A1 | MACROCYCLIC LIGANDS WITH PENDANT CHELATING MOIETIES AND COMPLEXES THEREOF | LUMIPHORE, INC. | 2024-02-29 | — | — | US | disclosed |
| US-11691997-B2 | Macrocycles | LUMIPHORE, INC. (US) | 2023-07-04 | — | — | US | disclosed |
| US-11691997-B2 | Macrocycles | LUMIPHORE, INC. (US) | 2023-07-04 | — | — | US | disclosed |
| EP-3129350-B1 | MACROCYCLES | LUMIPHORE INC (US) | 2021-10-27 | — | — | EP | disclosed |
| US-10434186-B2 | Functionalized linear ligands and complexes thereof | LUMIPHORE, INC. (US) | 2019-10-08 | — | — | US | disclosed |
| US-10352938-B2 | Macrocyclic HOPO chelators | LUMIPHORE, INC. (US) | 2019-07-16 | — | — | US | disclosed |
| US-10273256-B2 | Macrocycles | LUMIPHORE, INC. (US) | 2019-04-30 | — | — | US | disclosed |
| US-10239878-B2 | Macrocyclic ligands with pendant chelating moieties and complexes thereof | LUMIPHORE, INC. (US) | 2019-03-26 | — | — | US | disclosed |
| US-20180194766-A1 | MACROCYCLIC LIGANDS WITH PENDANT CHELATING MOIETIES AND COMPLEXES THEREOF | LUMIPHORE, INC. | 2018-07-12 | — | — | US | disclosed |
| US-20180194766-A1 | MACROCYCLIC LIGANDS WITH PENDANT CHELATING MOIETIES AND COMPLEXES THEREOF | LUMIPHORE, INC. | 2018-07-12 | — | — | US | disclosed |
| US-20170183365-A1 | MACROCYCLES | LUMIPHORE, INC. | 2017-06-29 | — | — | US | disclosed |
| US-20160320399-A1 | MACROCYCLIC HOPO CHELATORS | LUMIPHORE, INC. | 2016-11-03 | — | — | US | disclosed |
| US-9439984-B2 | Macrocycles | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2016-09-13 | — | — | US | disclosed |
| US-20160221971-A1 | DI-MACROCYCLES | LUMIPHORE, INC. (US) | 2016-08-04 | — | — | US | disclosed |
| US-9273059-B2 | Macrocyclic HOPO chelators | LUMIPHORE, INC. (US) | 2016-03-01 | — | — | US | disclosed |
| US-20150157746-A1 | MACROCYCLES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2015-06-11 | — | — | US | disclosed |
| US-20120214253-A1 | MACROCYCLIC HOPO CHELATORS | LUMIPHORE, INC. (US) | 2012-08-23 | — | — | US | disclosed |
| US-20120214253-A1 | MACROCYCLIC HOPO CHELATORS | LUMIPHORE, INC. (US) | 2012-08-23 | — | — | US | disclosed |
| US-20110189088-A1 | RADIOPHARMACEUTICAL COMPLEXES | LUMIPHORE, INC. (US) | 2011-08-04 | — | — | US | disclosed |
| US-20110189088-A1 | RADIOPHARMACEUTICAL COMPLEXES | LUMIPHORE, INC. (US) | 2011-08-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (13 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110189088-A1 | RADIOPHARMACEUTICAL COMPLEXES | SLC39A3, SLC30A5, SLC40A1 | MAPT 4451/4885NAMPT 1544/4885LMNA 4420/4885 |
| US-20160221971-A1 | DI-MACROCYCLES | DLD, NDC1, MCL1 | MAPT 1196/4885NAMPT 1212/4885LMNA 3243/4885 |
| US-11691997-B2 | Macrocycles | HCCS, ABCB7, AURKAIP1 | MAPT 1131/4885NAMPT 952/4885LMNA 3079/4885 |
| US-10434186-B2 | Functionalized linear ligands and complexes thereof | CLTB, CLTA, EPCAM | MAPT 1163/4885NAMPT 2225/4885LMNA 1626/4885 |
| US-20240067650-A1 | MACROCYCLIC LIGANDS WITH PENDANT CHELATING MOIETIES AND COMPLEXES THEREOF | TFRC, CLTC, SLC39A3 | MAPT 2173/4885NAMPT 797/4885LMNA 3330/4885 |
| US-20180194766-A1 | MACROCYCLIC LIGANDS WITH PENDANT CHELATING MOIETIES AND COMPLEXES THEREOF | TFRC, CLTC, SLC39A3 | MAPT 2173/4885NAMPT 797/4885LMNA 3330/4885 |
| US-10273256-B2 | Macrocycles | HCCS, ABCB7, AURKAIP1 | MAPT 1131/4885NAMPT 952/4885LMNA 3079/4885 |
| US-20170183365-A1 | MACROCYCLES | HCCS, ABCB7, AURKAIP1 | MAPT 1131/4885NAMPT 952/4885LMNA 3079/4885 |
| US-20160320399-A1 | MACROCYCLIC HOPO CHELATORS | PHPT1, SSB, CD69 | MAPT 2711/4885NAMPT 2987/4885LMNA 3821/4885 |
| US-10239878-B2 | Macrocyclic ligands with pendant chelating moieties and complexes thereof | TFRC, CLTC, SLC39A3 | MAPT 2173/4885NAMPT 797/4885LMNA 3330/4885 |
| US-20150157746-A1 | MACROCYCLES | SLC39A14, SLC39A3, SLC40A1 | MAPT 4228/4885NAMPT 1264/4885LMNA 3805/4885 |
| US-20120214253-A1 | MACROCYCLIC HOPO CHELATORS | PHPT1, SSB, CD69 | MAPT 2711/4885NAMPT 2987/4885LMNA 3821/4885 |
| US-10352938-B2 | Macrocyclic HOPO chelators | PHPT1, SSB, CD69 | MAPT 2711/4885NAMPT 2987/4885LMNA 3821/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.