Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 11/20 | 0.65 |
| ▸ | PGR | P06401 | 9/20 | 0.65 |
| ▸ | HIF1A | Q16665 | 6/20 | 0.65 |
| ▸ | LMNA | P02545 | 4/20 | 0.65 |
| ▸ | USP2 | O75604 | 3/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.65 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.65 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.65 |
| ▸ | NR1I2 | O75469 | 3/20 | 0.64 |
| ▸ | CNR1 | P21554 | 3/20 | 0.64 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.60 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | TNF | P01375 | 1/20 | 0.52 |
| ▸ | IL6 | P05231 | 1/20 | 0.52 |
| ▸ | SERPINA6 | P08185 | 1/20 | 0.52 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11296376 | 0.91 | NR3C1 (0.63) | NR3C1PGRHIF1ALMNAUSP2 | |
| SCHEMBL4222312 | 0.90 | NR3C1 (0.64) | NR3C1PGRHIF1ALMNAUSP2 | |
| SCHEMBL11561586 | 0.90 | NR3C1 (0.60) | NR3C1PGRHIF1ALMNAUSP2 | |
| SCHEMBL4222316 | 0.90 | NR3C1 (0.63) | NR3C1PGRHIF1ALMNAUSP2 | |
| SCHEMBL23892577 | 0.88 | NR3C1 (0.73) | NR3C1PGRHIF1ALMNAUSP2 | |
| SCHEMBL19393185 | 0.88 | NR3C1 (0.73) | NR3C1PGRHIF1ALMNAUSP2 | |
| SCHEMBL19681910 | 0.88 | NR3C1 (0.73) | NR3C1PGRHIF1ALMNAUSP2 | |
| SCHEMBL11054207 | 0.88 | NR3C1 (0.73) | NR3C1PGRHIF1ALMNAUSP2 | |
| SCHEMBL11045196 | 0.88 | NR3C1 (0.73) | NR3C1PGRHIF1ALMNAUSP2 | |
| SCHEMBL11045199 | 0.88 | NR3C1 (0.73) | NR3C1PGRHIF1ALMNAUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200046845-A1 | CYCLODEXTRIN-BASED POLYMERS FOR THERAPEUTIC DELIVERY | CERULEAN PHARMA INC. | 2020-02-13 | — | — | US | disclosed |
| US-20120213854-A1 | METHODS OF TREATING A SUBJECT AND RELATED PARTICLES, POLYMERS AND COMPOSITIONS | CERULEAN PHARMA INC. | 2012-08-23 | — | — | US | disclosed |
| US-20120213854-A1 | METHODS OF TREATING A SUBJECT AND RELATED PARTICLES, POLYMERS AND COMPOSITIONS | CERULEAN PHARMA INC. | 2012-08-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200046845-A1 | CYCLODEXTRIN-BASED POLYMERS FOR THERAPEUTIC DELIVERY | CDR2, DDOST, GALC | NR3C1 598/4885PGR 3603/4885HIF1A 4431/4885 |
| US-20120213854-A1 | METHODS OF TREATING A SUBJECT AND RELATED PARTICLES, POLYMERS AND COMPOSITIONS | HLA-DRB1, TSG101, IAPP | NR3C1 726/4885PGR 3157/4885HIF1A 2705/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.