Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 11/20 | 0.63 |
| ▸ | PGR | P06401 | 9/20 | 0.63 |
| ▸ | HIF1A | Q16665 | 6/20 | 0.63 |
| ▸ | LMNA | P02545 | 4/20 | 0.63 |
| ▸ | CNR1 | P21554 | 3/20 | 0.63 |
| ▸ | NR1I2 | O75469 | 3/20 | 0.63 |
| ▸ | USP2 | O75604 | 3/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.53 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.53 |
| ▸ | TNF | P01375 | 1/20 | 0.53 |
| ▸ | IL6 | P05231 | 1/20 | 0.53 |
| ▸ | SERPINA6 | P08185 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11561586 | 0.94 | NR3C1 (0.60) | NR3C1PGRHIF1ALMNACNR1 | |
| SCHEMBL11288654 | 0.92 | NR3C1 (0.71) | NR3C1PGRHIF1ALMNACNR1 | |
| SCHEMBL11566212 | 0.91 | NR3C1 (0.59) | NR3C1PGRHIF1ALMNACNR1 | |
| SCHEMBL11990602 | 0.91 | NR3C1 (0.65) | NR3C1PGRHIF1ALMNACNR1 | |
| SCHEMBL11584989 | 0.89 | PGR (0.68) | NR3C1PGRHIF1ALMNACNR1 | |
| SCHEMBL11586807 | 0.87 | PGR (0.64) | NR3C1PGRHIF1ALMNACNR1 | |
| SCHEMBL11586806 | 0.87 | PGR (0.64) | NR3C1PGRHIF1ALMNACNR1 | |
| SCHEMBL23892577 | 0.87 | NR3C1 (0.73) | NR3C1PGRHIF1ALMNACNR1 | |
| SCHEMBL11054207 | 0.87 | NR3C1 (0.73) | NR3C1PGRHIF1ALMNACNR1 | |
| SCHEMBL11045199 | 0.87 | NR3C1 (0.73) | NR3C1PGRHIF1ALMNACNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0000742-B1 | CORTICOIDS-17-ALKYLCARBONATES, PROCESS FOR THEIR PREPARATION AND PREPARATIONS CONTAINING THEM | HOECHST AKTIENGESELLSCHAFT (DE) | 1982-05-12 | — | — | EP | disclosed |