SCHEMBL1199470

SCHEMBL1199470

O=[N+]([O-])CCCCCCO

nearest known ligand 0.60

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.60
TDP1 Q9NUW8 1/20 0.60
LMNA P02545 3/20 0.40
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
BLM P54132 1/20 0.40
HBB P68871 1/20 0.40
HIF1A Q16665 1/20 0.40
GPR84 Q9NQS5 1/20 0.36
FFAR1 O14842 1/20 0.36
FFAR4 Q5NUL3 1/20 0.36
TSHR P16473 2/20 0.35
HSD17B10 Q99714 1/20 0.35
SMN1; SMN2 Q16637 2/20 0.30
KDM4E B2RXH2 1/20 0.30
CA5A P35218 1/20 0.30
CA5B Q9Y2D0 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2168216 1.00
SCHEMBL10950637 1.00 ALDH1A1 (0.60) ALDH1A1TDP1LMNAMEN1KMT2A
SCHEMBL28575007 1.00 ALDH1A1 (0.60) ALDH1A1TDP1LMNAMEN1KMT2A
SCHEMBL6381540 1.00 ALDH1A1 (0.60) ALDH1A1TDP1LMNAMEN1KMT2A
SCHEMBL28576746 1.00 ALDH1A1 (0.60) ALDH1A1TDP1LMNAMEN1KMT2A
SCHEMBL28914313 1.00 ALDH1A1 (0.60) ALDH1A1TDP1LMNAMEN1KMT2A
SCHEMBL8032226 1.00 ALDH1A1 (0.60) ALDH1A1TDP1LMNAMEN1KMT2A
SCHEMBL4238846 1.00 ALDH1A1 (0.60) ALDH1A1TDP1LMNAMEN1KMT2A
SCHEMBL2167079 0.97
SCHEMBL437912 0.88

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112911942-A Aqueous composition comprising omega-nitrooxy-1-alkanol 帝斯曼知识产权资产管理有限公司 2021-06-04 CN disclosed
US-9783833-B2 Biocatalytic methods to convert cyclohexane oxidation process waste streams to useful products INVISTA NORTH AMERICA S.A.R.L. (US) 2017-10-10 US disclosed
US-9775241-B2 Nanotube dispersants and dispersant free nanotube films therefrom UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2017-09-26 US disclosed
EP-2717864-A1 BIOPASSIVATING MEMBRANE STABILIZATION BY MEANS OF NITROCARBOXYLIC ACID-CONTAINING PHOSPHOLIPIDS IN PREPARATIONS AND COATINGS Dietz, Ulrich (DE) 2014-04-16 EP disclosed
US-20140099354-A1 BIOPASSIVATING MEMBRANE STABILIZATION BY MEANS OF NITROCARBOXYLIC ACID-CONTAINING PHOSPHOLIPIDS IN PREPARATIONS AND COATINGS Dietz, Ulrich (DE) 2014-04-10 US disclosed
US-8609873-B2 Process for making and using HOF.RCN THE SECRETARY OF STATE FOR DEFENSE IN HER BRITANNIC MAJESTY'S GOVERNMENT OF THE UNITED KINGDOM OF GREAT BRITAIN AND NORTHERN IRELAND (GB) 2013-12-17 US disclosed
WO-2012168342-A1 BIOPASSIVATING MEMBRANE STABILIZATION BY MEANS OF NITROCARBOXYLIC ACID-CONTAINING PHOSPHOLIPIDS IN PREPARATIONS AND COATINGS DIETZ ULRICH (DE) 2012-12-13 WO disclosed
CN-101172957-B Novel compound, synthetic method thereof and therapeutic usage GILEAD SCIENCES INC (US) 2012-11-14 CN disclosed
US-20110040092-A1 PROCESS FOR MAKING AND USING HOF.RCN THE SECRETARY OF STATE FOR DEFENSE (GB) 2011-02-17 US disclosed
EP-2188046-A2 A PROCESS FOR MAKING AND USING HYPOFLUOROUS ACID (HOF)/NITRILE (RCN) COMPLEXES . The Secretary of State For Defence (GB) 2010-05-26 EP disclosed
US-20050176758-A1 2-(hydroxy or methoxymethoxy)-4-(carboxy or alkoxycarbonyl)-5-(fluoro or hydrogen)-7-oxabicyclo(4.1.0)hept-3-ene chemical intermediates to neuraminidase inhibitors GILEAD SCIENCES, INC. 2005-08-11 US disclosed
CN-1185223-C Novel compounds, their synthesis and therapeutic use GILEAD SCIENCES INC (US) 2005-01-19 CN disclosed
US-6225341-B1 FOR INHIBITING NEURAMINIDASE; FOR THERAPY AND PROPHYLAXIS OF VIRUS INFECTION GILEAD SCIENCES, INC. 2001-05-01 US disclosed
EP-0759917-B1 NOVEL SELECTIVE INHIBITORS OF VIRAL OR BACTERIAL NEURAMINIDASES GILEAD SCIENCES INC (US) 2000-04-12 EP disclosed
CN-1147813-A Novel compounds, their synthesis and therapeutic use GILEAD SCIENCES INC (US) 1997-04-16 CN disclosed
WO-1996026933-A9 NOVEL SELECTIVE INHIBITORS OF VIRAL OR BACTERIAL NEURAMINIDASES 1996-11-28 WO disclosed
CN-86108089-A New tetrahydro isoquinoline derivative 1987-09-16 CN disclosed
EP-0229944-A2 Novel tetrahydroisoquinoline derivatives SYNTEX (U.S.A.) INC. (US) 1987-07-29 EP disclosed
US-4681889-A ANGINA, HYPERTENSION, CONGESTIVE HEART FAILURE SYNTEX (U.S.A.) INC. (US) 1987-07-21 US disclosed
US-4613606-A CARDIOVASCULAR DISORDERS SYNTEX (U.S.A.) INC. (US) 1986-09-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140099354-A1 BIOPASSIVATING MEMBRANE STABILIZATION BY MEANS OF NITROCARBOXYLIC ACID-CONTAINING PHOSPHOLIPIDS IN PREPARATIONS AND COATINGS PHOSPHO1, PTDSS1, LIPG ALDH1A1 2921/4885TDP1 2044/4885LMNA 338/4885
US-20110040092-A1 PROCESS FOR MAKING AND USING HOF.RCN HMOX2, FSCN1, POLN ALDH1A1 575/4885TDP1 2265/4885LMNA 3021/4885
US-20050176758-A1 2-(hydroxy or methoxymethoxy)-4-(carboxy or alkoxycarbonyl)-5-(fluoro or hydrogen)-7-oxabicyclo(4.1.0)hept-3-ene chemical intermediates to neuraminidase inhibitors NEU3, NEU1, NEU4 ALDH1A1 374/4885TDP1 2496/4885LMNA 1220/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.