SCHEMBL11995095

SCHEMBL11995095

Cc1ccccc1N1c2nccnc2N(C)[C@@H]1C

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.35
KDM4E B2RXH2 4/20 0.35
FLT3 P36888 2/20 0.35
GSK3B P49841 2/20 0.35
LMNA P02545 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
ATM Q13315 1/20 0.35
HPGD P15428 4/20 0.35
TDP1 Q9NUW8 3/20 0.35
TSHR P16473 3/20 0.33
MAPT P10636 1/20 0.33
ALOX15 P16050 1/20 0.33
MAPK1 P28482 1/20 0.33
HKDC1 Q2TB90 1/20 0.33
HSD17B10 Q99714 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
PTPN2 P17706 1/20 0.33
PTPN1 P18031 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16118393 1.00 ALDH1A1 (0.35) ALDH1A1KDM4EFLT3GSK3BLMNA
SCHEMBL16726497 1.00 ALDH1A1 (0.35) ALDH1A1KDM4EFLT3GSK3BLMNA
SCHEMBL12092103 0.88 GAA (0.36) ALDH1A1KDM4ELMNANPSR1MEN1
SCHEMBL17655189 0.86 KDM4E (0.38) ALDH1A1KDM4EFLT3GSK3BLMNA
SCHEMBL16726496 0.86 KDM4E (0.38) ALDH1A1KDM4EFLT3GSK3BLMNA
SCHEMBL24444108 0.86 KDM4E (0.38) ALDH1A1KDM4EFLT3GSK3BLMNA
SCHEMBL11995100 0.86 KDM4E (0.38) ALDH1A1KDM4EFLT3GSK3BLMNA
SCHEMBL11995106 0.86 KDM4E (0.38) ALDH1A1KDM4EFLT3GSK3BLMNA
SCHEMBL16726495 0.86 KDM4E (0.38) ALDH1A1KDM4EFLT3GSK3BLMNA
SCHEMBL16420320 0.85 GAA (0.37) ALDH1A1KDM4EHPGDPTPN2PTPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 368 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12035618-B2 Electroluminescent devices UNIVERSAL DISPLAY CORPORATION (US) 2024-07-09 US disclosed
US-12035618-B2 Electroluminescent devices UNIVERSAL DISPLAY CORPORATION (US) 2024-07-09 US disclosed
US-20240224782-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2024-07-04 US disclosed
US-20240218004-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2024-07-04 US disclosed
US-20240224783-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2024-07-04 US disclosed
US-20240224783-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2024-07-04 US disclosed
US-20240209013-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2024-06-27 US disclosed
US-12022727-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2024-06-25 US disclosed
US-12022727-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2024-06-25 US disclosed
US-20240074301-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2024-02-29 US disclosed
US-20130221332-A1 NOVEL HOST COMPOUNDS FOR RED PHOSPHORESCENT OLEDS UNIVERSAL DISPLAY CORPORATION (US) 2013-08-29 US disclosed
US-20130175507-A1 Novel Heterocyclic Host Materials UNIVERSAL DISPLAY CORPORATION (US) 2013-07-11 US disclosed
US-20130119353-A1 TRIPHENYLENE SILANE HOSTS UNIVERSAL DISPLAY CORPORATION (US) 2013-05-16 US disclosed
US-8409729-B2 Host materials for phosphorescent OLEDs UNIVERSAL DISPLAY CORPORATION (US) 2013-04-02 US disclosed
US-20130026909-A1 HOST MATERIALS FOR PHOSPHORESCENT OLEDS UNIVERSAL DISPLAY CORPORATION (US) 2013-01-31 US disclosed
US-20130015432-A1 INORGANIC HOSTS IN OLEDS UNIVERSAL DISPLAY CORPORATION (US) 2013-01-17 US disclosed
US-20120298966-A1 Host materials for oled UNIVERSAL DISPLAY CORPORATION (US) 2012-11-29 US disclosed
US-20120256169-A1 SUBSTITUTED OLIGOAZACARBAZOLES FOR LIGHT EMITTING DIODES UNIVERSAL DISPLAY CORPORATION (US) 2012-10-11 US disclosed
US-20120228583-A1 PYRIDYL CARBENE PHOSPHORESCENT EMITTERS UNIVERSAL DISPLAY CORPORATION (US) 2012-09-13 US disclosed
US-20120212125-A1 RUTHENIUM CARBENE COMPLEXES FOR OLED MATERIAL UNIVERSAL DISPLAY CORPORATION 2012-08-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (14 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120212125-A1 RUTHENIUM CARBENE COMPLEXES FOR OLED MATERIAL OCIAD2, OCIAD1, ORC3 ALDH1A1 3990/4885KDM4E 4525/4885FLT3 3759/4885
US-20120298966-A1 Host materials for oled OCIAD2, OCIAD1, OSBP2 ALDH1A1 3522/4885KDM4E 3086/4885FLT3 1683/4885
US-20130175507-A1 Novel Heterocyclic Host Materials OCIAD2, OCIAD1, ORC3 ALDH1A1 3435/4885KDM4E 3443/4885FLT3 2892/4885
US-20130119353-A1 TRIPHENYLENE SILANE HOSTS OCIAD2, OCIAD1, YAP1 ALDH1A1 3482/4885KDM4E 3627/4885FLT3 1709/4885
US-12035618-B2 Electroluminescent devices ELAVL1, ELAVL3, JUND ALDH1A1 1948/4885KDM4E 3586/4885FLT3 4108/4885
US-20130026909-A1 HOST MATERIALS FOR PHOSPHORESCENT OLEDS OSBP2, OCIAD2, OCIAD1 ALDH1A1 3992/4885KDM4E 3835/4885FLT3 2223/4885
US-20120256169-A1 SUBSTITUTED OLIGOAZACARBAZOLES FOR LIGHT EMITTING DIODES OXA1L, ORC3, OR10J3 ALDH1A1 303/4885KDM4E 3469/4885FLT3 2840/4885
US-20240074301-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES ICOSLG, OCIAD2, OSBP ALDH1A1 658/4885KDM4E 4314/4885FLT3 3345/4885
US-20240224783-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, ICOSLG ALDH1A1 149/4885KDM4E 3179/4885FLT3 3182/4885
US-20240209013-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, SSB, L1CAM ALDH1A1 419/4885KDM4E 2423/4885FLT3 3083/4885
US-20120228583-A1 PYRIDYL CARBENE PHOSPHORESCENT EMITTERS PAICS, PIR, NUDC ALDH1A1 3390/4885KDM4E 2901/4885FLT3 420/4885
US-12022727-B2 Organic electroluminescent materials and devices OCIAD1, OSBP, OCIAD2 ALDH1A1 175/4885KDM4E 4507/4885FLT3 4402/4885
US-20240224782-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES RER1, OCIAD2, OCIAD1 ALDH1A1 617/4885KDM4E 2979/4885FLT3 2049/4885
US-20240218004-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD1, OCIAD2, CCND2 ALDH1A1 497/4885KDM4E 1684/4885FLT3 3441/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.