SCHEMBL16726495

SCHEMBL16726495

Cc1ccccc1N1c2ncccc2N(C)[C@H]1C

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.38
ALDH1A1 P00352 4/20 0.38
HPGD P15428 3/20 0.38
TDP1 Q9NUW8 3/20 0.38
MAPT P10636 1/20 0.38
ALOX15 P16050 1/20 0.38
TSHR P16473 1/20 0.38
MAPK1 P28482 1/20 0.38
HKDC1 Q2TB90 1/20 0.38
HSD17B10 Q99714 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
FLT3 P36888 1/20 0.37
GSK3B P49841 1/20 0.37
NPSR1 Q6W5P4 2/20 0.37
ADORA3 P0DMS8 1/20 0.35
ADORA2A P29274 1/20 0.35
ADORA1 P30542 1/20 0.35
GAA P10253 2/20 0.35
ALOX12 P18054 1/20 0.35
NOS3 P29474 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11995100 1.00 KDM4E (0.38) KDM4EALDH1A1HPGDTDP1MAPT
SCHEMBL24444108 1.00 KDM4E (0.38) KDM4EALDH1A1HPGDTDP1MAPT
SCHEMBL12092099 0.88 GAA (0.40) KDM4EALDH1A1HPGDTDP1MAPT
SCHEMBL16726496 0.88 KDM4E (0.38) KDM4EALDH1A1HPGDTDP1MAPT
SCHEMBL17655189 0.88 KDM4E (0.38) KDM4EALDH1A1HPGDTDP1MAPT
SCHEMBL11995106 0.88 KDM4E (0.38) KDM4EALDH1A1HPGDTDP1MAPT
SCHEMBL23998675 0.87 ALDH1A1 (0.41) KDM4EALDH1A1HPGDTDP1MAPT
SCHEMBL17014643 0.87 CYP17A1 (0.34) KDM4EALDH1A1HPGDTDP1MAPK1
SCHEMBL17014639 0.87 CYP2A6 (0.33) KDM4EALDH1A1HPGDADORA3ADORA2A
SCHEMBL11995095 0.86 ALDH1A1 (0.35) KDM4EALDH1A1HPGDTDP1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220194956-A1 ORGANIC ELECTROLUMINESCENT MATERIAL AND DEVICE THEREOF Beijing Summer Sprout Technology Co., Ltd. (CN) 2022-06-23 US disclosed
US-20220199916-A1 ORGANIC ELECTROLUMINESCENT DEVICE Beijing Summer Sprout Technology Co., Ltd. (CN) 2022-06-23 US disclosed
EP-3220441-B1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORP (US) 2020-04-22 EP disclosed
US-10033000-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2018-07-24 US disclosed
US-10033000-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2018-07-24 US disclosed
US-9905784-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2018-02-27 US disclosed
US-9905784-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2018-02-27 US disclosed
EP-3220441-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES Universal Display Corporation (US) 2017-09-20 EP disclosed
EP-2874192-B1 Organic eletroluminescent materials and devices UNIVERSAL DISPLAY CORP (US) 2017-05-10 EP disclosed
EP-2874195-B1 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORP (US) 2017-05-03 EP disclosed
US-20150137095-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2015-05-21 US disclosed
US-20150137096-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2015-05-21 US disclosed
US-20150137095-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2015-05-21 US disclosed
US-20150137096-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2015-05-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10033000-B2 Organic electroluminescent materials and devices LSM8, OPRM1, OXER1 KDM4E 3500/4885ALDH1A1 962/4885HPGD 2836/4885
US-20220194956-A1 ORGANIC ELECTROLUMINESCENT MATERIAL AND DEVICE THEREOF PIEZO1, LEF1, TMEM109 KDM4E 2399/4885ALDH1A1 119/4885HPGD 1785/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.