Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC40A1 | Q9NP59 | 13/20 | 1.00 |
| ▸ | MEN1 | O00255 | 5/20 | 0.77 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.77 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.77 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.73 |
| ▸ | POLB | P06746 | 1/20 | 0.73 |
| ▸ | LMNA | P02545 | 1/20 | 0.73 |
| ▸ | TP53 | P04637 | 1/20 | 0.73 |
| ▸ | MAPT | P10636 | 1/20 | 0.73 |
| ▸ | HPGD | P15428 | 1/20 | 0.73 |
| ▸ | TSHR | P16473 | 1/20 | 0.73 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.73 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.73 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.73 |
| ▸ | GLO1 | Q04760 | 3/20 | 0.66 |
| ▸ | CKS1B | P61024 | 1/20 | 0.64 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.64 |
| ▸ | NFKBIA | P25963 | 1/20 | 0.61 |
| ▸ | RELA | Q04206 | 1/20 | 0.61 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7197593 | 0.89 | SLC40A1 (1.00) | SLC40A1MEN1KMT2ATDP1CXCR2 | |
| SCHEMBL13633886 | 0.87 | MEN1 (1.00) | SLC40A1MEN1KMT2ATDP1CXCR2 | |
| SCHEMBL11995659 | 0.85 | SLC40A1 (1.00) | SLC40A1MEN1KMT2ATDP1CXCR2 | |
| SCHEMBL22076984 | 0.85 | MEN1 (1.00) | SLC40A1MEN1KMT2ATDP1CXCR2 | |
| SCHEMBL1505430 | 0.85 | KMT2A (1.00) | SLC40A1MEN1KMT2ATDP1CXCR2 | |
| SCHEMBL29575795 | 0.85 | KMT2A (1.00) | SLC40A1MEN1KMT2ATDP1CXCR2 | |
| SCHEMBL4489024 | 0.84 | SLC40A1 (0.77) | SLC40A1MEN1KMT2ATDP1CXCR2 | |
| SCHEMBL4489851 | 0.84 | MEN1 (0.84) | SLC40A1MEN1KMT2ATDP1CXCR2 | |
| SCHEMBL22111633 | 0.84 | MEN1 (0.84) | SLC40A1MEN1KMT2ATDP1CXCR2 | |
| SCHEMBL1110190 | 0.84 | SLC40A1 (0.77) | SLC40A1MEN1KMT2ATDP1CXCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9102688-B2 | Sulfonaminoquinoline hepcidin antagonists | VIFOR (INTERNATIONAL) AG (CH) | 2015-08-11 | — | — | US | disclosed |
| US-9102688-B2 | Sulfonaminoquinoline hepcidin antagonists | VIFOR (INTERNATIONAL) AG (CH) | 2015-08-11 | — | — | US | disclosed |
| US-20140364424-A1 | Novel Sulfonaminoquinoline Hepcidin Antagonists | VIFOR (INTERNATIONAL) AG (CH) | 2014-12-11 | — | — | US | disclosed |
| US-20140364424-A1 | Novel Sulfonaminoquinoline Hepcidin Antagonists | VIFOR (INTERNATIONAL) AG (CH) | 2014-12-11 | — | — | US | disclosed |
| US-20120214803-A1 | Novel Sulfonaminoquinoline Hepcidin Antagonists | VIFOR (INTERNATIONAL) AG (CH) | 2012-08-23 | — | — | US | disclosed |
| US-20120214803-A1 | Novel Sulfonaminoquinoline Hepcidin Antagonists | VIFOR (INTERNATIONAL) AG (CH) | 2012-08-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120214803-A1 | Novel Sulfonaminoquinoline Hepcidin Antagonists | HAMP, SLC40A1, FTH1 | SLC40A1 2/4885MEN1 2680/4885KMT2A 3298/4885 |
| US-20140364424-A1 | Novel Sulfonaminoquinoline Hepcidin Antagonists | HAMP, SLC40A1, FTH1 | SLC40A1 2/4885MEN1 2680/4885KMT2A 3298/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.