Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | NOS1 | P29475 | 2/20 | 0.43 |
| ▸ | IDO1 | P14902 | 14/20 | 0.38 |
| ▸ | HTT | P42858 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.38 |
| ▸ | ATP1A1 | P05023 | 1/20 | 0.37 |
| ▸ | ATP1B1 | P05026 | 1/20 | 0.37 |
| ▸ | ATP1A3 | P13637 | 1/20 | 0.37 |
| ▸ | ATP1B2 | P14415 | 1/20 | 0.37 |
| ▸ | ATP1A2 | P50993 | 1/20 | 0.37 |
| ▸ | ATP1B3 | P54709 | 1/20 | 0.37 |
| ▸ | FXYD2 | P54710 | 1/20 | 0.37 |
| ▸ | ATP1A4 | Q13733 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | NOS3 | P29474 | 1/20 | 0.36 |
| ▸ | NOS2 | P35228 | 1/20 | 0.36 |
| ▸ | SLC11A2 | P49281 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14281051 | 0.84 | HPGD (0.37) | MAPTHTTLMNASMN1; SMN2HPGD | |
| SCHEMBL1121587 | 0.72 | HPGD (0.41) | MAPTHTTLMNASMN1; SMN2HPGD | |
| SCHEMBL2041229 | 0.69 | HPGD (0.39) | MAPTHTTSMN1; SMN2HPGD | |
| SCHEMBL15572842 | 0.68 | HPGD (0.38) | MAPTHTTLMNASMN1; SMN2HPGD | |
| SCHEMBL22275784 | 0.68 | MAPT (0.55) | MAPTNOS1IDO1HTTLMNA | |
| Bromide SCHEMBL20918047 | 0.66 | MAPT (0.53) | MAPTNOS1IDO1HTTLMNA | |
| SCHEMBL24133841 | 0.64 | CYP2A6 (0.56) | MAPTNOS1IDO1HTTLMNA | |
| SCHEMBL14930463 | 0.64 | SMN1; SMN2 (0.43) | MAPTHTTSMN1; SMN2HPGD | |
| SCHEMBL5450413 | 0.62 | NOS1 (1.00) | NOS1IDO1NOS3NOS2SLC11A2 | |
| SCHEMBL3121683 | 0.62 | HPGD (0.58) | MAPTHTTLMNASMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110046142-A1 | ANTIBIOTIC COMPOUNDS | NORTHEASTERN UNIVERSITY (US) | 2011-02-24 | — | — | US | disclosed |
| US-20080027044-A1 | Prodrug antibiotic screens | NORTHEASTERN UNIVERSITY | 2008-01-31 | — | — | US | disclosed |
| US-20080027044-A1 | Prodrug antibiotic screens | NORTHEASTERN UNIVERSITY | 2008-01-31 | — | — | US | disclosed |
| US-20080027044-A1 | Prodrug antibiotic screens | NORTHEASTERN UNIVERSITY | 2008-01-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110046142-A1 | ANTIBIOTIC COMPOUNDS | AADAC, SPOUT1, NRDC | MAPT 4110/4885NOS1 1741/4885IDO1 1926/4885 |
| US-20080027044-A1 | Prodrug antibiotic screens | O60361, PGLS, GUSB | MAPT 4398/4885NOS1 615/4885IDO1 832/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.