SCHEMBL120029

SCHEMBL120029

[CH2]CCCCc1ccc(O)c(OC)c1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 2/20 0.65
TSHR P16473 2/20 0.65
MAPK1 P28482 1/20 0.65
LMNA P02545 1/20 0.63
GLA P06280 1/20 0.63
PTPN1 P18031 2/20 0.61
CALM1 P0DP23 1/20 0.60
MTNR1A P48039 1/20 0.58
MTNR1B P49286 1/20 0.58
ALOX5 P09917 3/20 0.57
ALDH1A1 P00352 2/20 0.57
CYP3A4 P08684 1/20 0.57
AR P10275 1/20 0.57
PTGS1 P23219 1/20 0.57
TRPM8 Q7Z2W7 1/20 0.57
TUBB4A P04350 1/20 0.56
TUBB P07437 1/20 0.56
TUBA3C P0DPH7 1/20 0.56
TUBA1B P68363 1/20 0.56
TUBA4A P68366 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9281549 0.91 TAAR1 (0.76) TAAR1TSHRMAPK1LMNAGLA
SCHEMBL1485966 0.88 TAAR1 (0.71) TAAR1TSHRMAPK1LMNAGLA
SCHEMBL5072123 0.88 TAAR1 (0.76) TAAR1TSHRMAPK1LMNAGLA
SCHEMBL19545805 0.86 TAAR1 (0.69) TAAR1TSHRMAPK1LMNAGLA
SCHEMBL10683411 0.86 ALOX15 (0.70) TAAR1TSHRMAPK1LMNAGLA
SCHEMBL6566912 0.85 HTR1A (0.69) TAAR1TSHRMAPK1LMNAGLA
SCHEMBL3158703 0.85 TAAR1 (0.67) TAAR1TSHRMAPK1LMNAGLA
SCHEMBL7186374 0.84 ATM (0.59) ALDH1A1CYP3A4TUBB4ATUBBTUBA3C
SCHEMBL29604390 0.84 PTPN1 (0.82) TAAR1TSHRMAPK1LMNAGLA
SCHEMBL17780116 0.84 PTPN1 (0.82) TAAR1TSHRMAPK1LMNAGLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 70 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11123272-B2 Cosmetic blends SYMRISE AG (DE) 2021-09-21 US claimed
CN-110025496-A A kind of sorbefacient skin care item and preparation method thereof 烟台哈美医疗科技有限公司 2019-07-19 CN claimed
CN-109646379-A A kind of thermal sensation plant footbath liquor and preparation method thereof 广东暨晴生物医药科技有限公司 2019-04-19 CN claimed
CN-108078842-A A kind of proton pump kudzu root nutrient Essence and its preparation method and application 陈芳芳 2018-05-29 CN claimed
US-20160206553-A1 COLD-WARM PLASTER ALTERGON S.A. (CH) 2016-07-21 US claimed
US-20240130957-A1 EXTRACTS OF ISOCHRYSIS SPECIES/TISOCHRYSIS SPECIES SYMRISE AG (DE) 2024-04-25 US disclosed
US-11622920-B2 Delivery system for active agents SYMRISE AG (DE) 2023-04-11 US disclosed
CN-114796375-A Pain-relieving and collateral-activating oil for rheumatism 金中北 2022-07-29 CN disclosed
CN-114522118-A Foaming type facial cleanser with warming effect and preparation method thereof 诺斯贝尔化妆品股份有限公司 2022-05-24 CN disclosed
EP-3730124-A1 SOLID COSMETIC MITSUBISHI PENCIL COMPANY, LIMITED (JP) 2020-10-28 EP disclosed
CN-110269926-A Middle benefit gas, which is relaxed, warms up composition and its preparation method and application 深圳市容大生物技术有限公司 2019-09-24 CN disclosed
CN-110168038-A Methyl menthol derivative and cold feeling agent composition containing it 高砂香料工业株式会社 2019-08-23 CN disclosed
US-20060269500-A1 Topical warming composition TAKASAGO INTERNATIONAL CORP. (USA) (US) 2006-11-30 US disclosed
CN-1805728-A Shampoo and body detergent composition TAKASAGO PERFUMERY CO LTD (JP) 2006-07-19 CN disclosed
EP-1649759-A1 FLAVOR ENHANCER, FOOD OR BEVERAGE CONTAINING THE FLAVOR ENHANCER, AND METHOD OF FLAVOR ENHANCEMENT Takasago International Corporation (JP) 2006-04-26 EP disclosed
CN-1758896-A Composition comprising zinc-containing layered material having relatively high zinc lability PROCTER & GAMBLE (US) 2006-04-12 CN disclosed
CN-1758895-A Use of zinc-containing layered materials to increase pyrithione activity or polyvalent metal salt activity of pyrithione PROCTER & GAMBLE (US) 2006-04-12 CN disclosed
CN-1758893-A Composition comprising particulate zinc material having defined crystallite size PROCTER & GAMBLE (US) 2006-04-12 CN disclosed
CN-1646124-A Use of substances with zinc ionophore properties PROCTER & GAMBLE ARCH CHEMICAL (US) 2005-07-27 CN disclosed
US-6570010-B2 Comprises a cyclodextrin or a branched cyclodextrin and a vanillyl alcohol derivative, such as vanillyl-n butyl ether TAKASAGO INTERNATIONAL CORPORATION (JP) 2003-05-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11123272-B2 Cosmetic blends TRPA1, TRPV3, TRPV1 TAAR1 182/4885TSHR 3909/4885MAPK1 2903/4885
US-20060269500-A1 Topical warming composition CUTA, NACA, LSM14A TAAR1 3783/4885TSHR 3612/4885MAPK1 4221/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.