SCHEMBL120127

SCHEMBL120127

CC(O)CC(C(=O)O)C1CC(C)CCC1C(C)C

nearest known ligand 0.45

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 3/20 0.45
TRPM8 Q7Z2W7 4/20 0.43
TRPA1 O75762 2/20 0.43
CYP19A1 P11511 2/20 0.40
ALDH1A1 P00352 2/20 0.37
HPGD P15428 1/20 0.36
KCNA5 P22460 1/20 0.35
TRPV1 Q8NER1 3/20 0.35
LMNA P02545 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19209892 0.84 EPHX1 (0.47) EPHX1TRPM8TRPA1CYP19A1ALDH1A1
SCHEMBL4312363 0.84 EPHX1 (0.47) EPHX1TRPM8TRPA1CYP19A1ALDH1A1
SCHEMBL15468048 0.83 EPHX1 (0.44) EPHX1TRPM8TRPA1CYP19A1ALDH1A1
SCHEMBL584085 0.83 EPHX1 (0.46) EPHX1TRPM8TRPA1CYP19A1ALDH1A1
SCHEMBL18280698 0.81 EPHX1 (0.45) EPHX1TRPM8TRPA1CYP19A1ALDH1A1
SCHEMBL8743483 0.80 EPHX1 (0.50) EPHX1TRPM8TRPA1ALDH1A1HPGD
SCHEMBL38660082 0.80 EPHX1 (0.50) EPHX1TRPM8TRPA1ALDH1A1HPGD
SCHEMBL583665 0.80 EPHX1 (0.44) EPHX1TRPM8TRPA1CYP19A1KCNA5
SCHEMBL4314193 0.79 EPHX1 (0.43) EPHX1TRPM8TRPA1
SCHEMBL851820 0.78 EPHX1 (0.51) EPHX1TRPM8TRPA1ALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 298 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240041726-A1 FOAMABLE COMPOSITION, USE THEREOF, AND PROCESS FOR ITS PREPARATION CHATTEM, INC. 2024-02-08 US claimed
EP-4231985-A1 FOAMABLE COMPOSITION, USE THEREOF, AND PROCESS FOR ITS PREPARATION Chattem, Inc. (US) 2023-08-30 EP claimed
CN-116322613-A Foamable composition, use thereof and method for the production thereof 查泰姆公司 2023-06-23 CN claimed
WO-2022087343-A1 FOAMABLE COMPOSITION, USE THEREOF, AND PROCESS FOR ITS PREPARATION CHATTEM, INC. (US) 2022-04-28 WO claimed
EP-3169365-A2 COMPOUNDS AND METHODS FOR THE TREATMENT OF ITCH Westfälische Wilhelms-Universität Münster (DE) 2017-05-24 EP claimed
EP-3003031-A1 COATED PARTICLES AND COMPOSITIONS COMPRISING SAME Vyome Biosciences Pvt Ltd (IN) 2016-04-13 EP claimed
WO-2015169884-A2 COMPOUNDS AND METHODS FOR THE TREATMENT OF ITCH WESTFAELISCHE WILHELMS-UNIVERSITAET MUENSTER (DE) 2015-11-12 WO claimed
WO-2014195872-A1 COATED PARTICLES AND COMPOSITIONS COMPRISING SAME VYOME BIOSCIENCES PVT. LTD. (IN) 2014-12-11 WO claimed
EP-2355665-A1 SENSATE- PLATED SANDING COMPOSITION AND PRODUCTS MADE THEREFROM Kraft Foods Global Brands LLC (US) 2011-08-17 EP claimed
WO-2010056697-A1 SENSATE- PLATED SANDING COMPOSITION AND PRODUCTS MADE THEREFROM CADBURY ADAMS USA LLC (US) 2010-05-20 WO claimed
EP-1973422-A1 COMPOSITIONS PROVIDING A HEATING SENSATION FOR ORAL OR DERMAL DELIVERY Cadbury Adams USA LLC (US) 2008-10-01 EP claimed
WO-2007126430-A1 COMPOSITIONS PROVIDING A HEATING SENSATION FOR ORAL OR DERMAL DELIVERY CADBURY ADAMS USA LLC (US) 2007-11-08 WO claimed
WO-2006127738-A9 COMPRESSIBLE CHEWING GUMS FOR DELIVERY OF ACTIVES CADBURY ADAMS USA LLC (US) 2007-05-31 WO claimed
WO-2006127738-A2 COMPRESSIBLE CHEWING GUMS FOR DELIVERY OF ACTIVES CADBURY ADAMS USA LLC (US) 2006-11-30 WO claimed
WO-2006127740-A2 INDICIA-BEARING PACKAGE FOR DELIVERY SYSTEMS FOR MANAGING RELEASE OF SWEETENERS, SENSATES, FUNCTIONAL INGREDIENTS, FOOD ACIDS AND FLAVORS IN A COMPRESSIBLE GUM SYSTEM CADBURY ADAMS USA LLC (US) 2006-11-30 WO claimed
US-6838106-B2 Warming composition for food and drink or for oral care preparation TAKASAGO INTERNATIONAL CORPORATION (JP) 2005-01-04 US claimed
EP-4364577-A2 CENTER-FILLED CONFECTIONERY PRODUCT; COATED PRODUCT; AND METHODS OF MAKING Intercontinental Great Brands LLC (US) 2024-05-08 EP disclosed
US-20240099948-A1 Compositions Comprising Silicon Dioxide-Based Particles Including One or More Agents COLABS INT'L CORP. (US) 2024-03-28 US disclosed
EP-1215257-A2 Warming composition Takasago International Corporation (JP) 2002-06-19 EP disclosed
EP-1215258-A2 Waming composition for food and drink or for oral care preparation Takasago International Corporation (JP) 2002-06-19 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240099948-A1 Compositions Comprising Silicon Dioxide-Based Particles Including One or More Agents MSN, LIPE, CUTA EPHX1 1562/4885TRPM8 1853/4885TRPA1 263/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.