SCHEMBL583665

SCHEMBL583665

CC1CCC(C(C)C)C(C(CCC(=O)O)C(=O)O)C1

nearest known ligand 0.44

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 3/20 0.44
TRPM8 Q7Z2W7 4/20 0.42
TRPA1 O75762 2/20 0.42
CYP1A2 P05177 2/20 0.38
CYP2C19 P33261 1/20 0.35
KCNA5 P22460 1/20 0.35
TRPV1 Q8NER1 2/20 0.35
CYP19A1 P11511 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18280698 0.86 EPHX1 (0.45) EPHX1TRPM8TRPA1KCNA5TRPV1
SCHEMBL15468048 0.85 EPHX1 (0.44) EPHX1TRPM8TRPA1KCNA5TRPV1
SCHEMBL584085 0.84 EPHX1 (0.46) EPHX1TRPM8TRPA1KCNA5TRPV1
SCHEMBL4314193 0.84 EPHX1 (0.43) EPHX1TRPM8TRPA1
SCHEMBL19209892 0.83 EPHX1 (0.47) EPHX1TRPM8TRPA1KCNA5TRPV1
SCHEMBL4312363 0.83 EPHX1 (0.47) EPHX1TRPM8TRPA1KCNA5TRPV1
SCHEMBL21380222 0.81 EPHX1 (0.43) EPHX1TRPM8TRPA1KCNA5TRPV1
SCHEMBL120127 0.80 EPHX1 (0.45) EPHX1TRPM8TRPA1KCNA5TRPV1
SCHEMBL38660082 0.79 EPHX1 (0.50) EPHX1TRPM8TRPA1KCNA5TRPV1
SCHEMBL8743483 0.79 EPHX1 (0.50) EPHX1TRPM8TRPA1KCNA5TRPV1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 514 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3908266-B1 LIQUID COMPOSITIONS KENVUE BRANDS LLC (US) 2025-10-15 EP claimed
US-20240058243-A1 A METHOD FOR FIGHTING MICROORGANISMS USING MENTHOL DERIVATIVES SYMRISE AG (DE) 2024-02-22 US claimed
EP-3494104-B1 WARMING SENSATION COMPOUNDS TAKASAGO PERFUMERY CO LTD (JP) 2023-11-15 EP claimed
EP-4259287-A1 A METHOD FOR FIGHTING MICROORGANISMS USING MENTHOL DERIVATIVES Symrise AG (DE) 2023-10-18 EP claimed
EP-3081207-B1 USE OF A LIPOSOME COMPOSITION SYMRISE AG (DE) 2022-09-21 EP claimed
WO-2022122144-A1 A METHOD FOR FIGHTING MICROORGANISMS USING MENTHOL DERIVATIVES SYMRISE AG (DE) 2022-06-16 WO claimed
EP-2793877-B2 CHEWING GUM PRODUCTS CONTAINING [(2-ISOPROPYL-5-METHYL-CYCLOHEXANECARBONYL)-AMINO]-ACETIC ACID ISOPROPYL ESTER WRIGLEY W M JUN CO (US) 2022-05-04 EP claimed
EP-3687311-A1 AMIDES FOR GENERATING A TRIGEMINAL EFFECT Symrise AG (DE) 2020-08-05 EP claimed
EP-3193848-B1 PRODUCTS CONTAINING NOVEL FLAVOR COMPOSITION WRIGLEY W M JUN CO (US) 2020-04-15 EP claimed
EP-3142499-B1 HOMOVANILLIC ACID ESTERS, IN PARTICULAR FOR ACHIEVING AN IMPRESSION OF HEAT AND/OR SPICINESS SYMRISE AG (DE) 2019-10-30 EP claimed
EP-2008530-B1 Aroma composition for reducing or suppressing unwanted bitter and astringent impressions SYMRISE AG (DE) 2011-01-19 EP claimed
EP-1718164-B1 CONFECTIONS CONTAINING A BLEND OF PHYSILOGICAL COOLING AGENTS WRIGLEY W M JUN CO (US) 2010-09-29 EP claimed
US-20100226864-A1 ALKYL-SUBSTITUTED TETRAHYDROPYRANS AS FLAVORING SUBSTANCES SYMRISE GMBH & CO. KG (DE) 2010-09-09 US claimed
EP-1534252-B1 BREATH FRESHENING AND ORAL CLEANSING PRODUCT USING CARDAMOM OIL WRIGLEY W M JUN CO (US) 2010-06-30 EP claimed
EP-1896557-B1 FLAVOR AND FRAGRANCE COMPOSITION TAKASAGO PERFUMERY CO LTD (JP) 2010-05-05 EP claimed
EP-2168957-A2 Alkyl-substituted tetrahydropyranes as aromatic materials Symrise GmbH & Co. KG (DE) 2010-03-31 EP claimed
EP-2008530-A1 Aroma composition for reducing or suppressing unwanted bitter and astringent impressions Symrise GmbH & Co. KG (DE) 2008-12-31 EP claimed
WO-2008049651-A1 PERFORMANCE-ENHANCED COSMETIC COMPOSITIONS WITH PURINE AND/OR PURINE DERIVATIVES HENKEL AG & CO. KGAA (DE) 2008-05-02 WO claimed
EP-1880705-A2 Brightening and/or colouring composition with improved product sensation HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2008-01-23 EP claimed
EP-1446019-B1 WATER CONTINUOUS FOOD PRODUCT WITH COOLING FLAVOUR UNILEVER NV (NL) 2007-03-14 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100226864-A1 ALKYL-SUBSTITUTED TETRAHYDROPYRANS AS FLAVORING SUBSTANCES TAS1R3, TAS2R10, TAS2R50 EPHX1 2547/4885TRPM8 131/4885TRPA1 25/4885
US-20240058243-A1 A METHOD FOR FIGHTING MICROORGANISMS USING MENTHOL DERIVATIVES MGLL, GCDH, GK EPHX1 1246/4885TRPM8 84/4885TRPA1 187/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.