Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERCC5 | P28715 | 1/20 | 0.65 |
| ▸ | FEN1 | P39748 | 1/20 | 0.65 |
| ▸ | RAB9A | P51151 | 4/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.64 |
| ▸ | NPC1 | O15118 | 3/20 | 0.64 |
| ▸ | MEN1 | O00255 | 3/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.64 |
| ▸ | LMNA | P02545 | 2/20 | 0.64 |
| ▸ | POLB | P06746 | 2/20 | 0.64 |
| ▸ | GSK3B | P49841 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 5/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | CES2 | O00748 | 1/20 | 0.54 |
| ▸ | CES1 | P23141 | 1/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.53 |
| ▸ | DAO | P14920 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL711360 | 0.87 | RAB9A (0.75) | ERCC5FEN1RAB9AALDH1A1NPC1 | |
| SCHEMBL5188799 | 0.82 | ALDH1A1 (0.81) | ERCC5FEN1RAB9AALDH1A1NPC1 | |
| SCHEMBL4341460 | 0.82 | ERCC5 (0.72) | ERCC5FEN1RAB9AALDH1A1NPC1 | |
| SCHEMBL1476817 | 0.81 | KMT2A (0.71) | ERCC5FEN1RAB9AALDH1A1NPC1 | |
| SCHEMBL1547840 | 0.80 | ERCC5 (0.65) | ERCC5FEN1RAB9AALDH1A1NPC1 | |
| SCHEMBL355263 | 0.79 | — | — | |
| SCHEMBL4765892 | 0.79 | — | — | |
| SCHEMBL2216212 | 0.79 | ALDH1A1 (1.00) | ERCC5FEN1RAB9AALDH1A1NPC1 | |
| SCHEMBL31291382 | 0.78 | ERCC5 (1.00) | ERCC5FEN1RAB9AALDH1A1NPC1 | |
| SCHEMBL28459884 | 0.78 | ERCC5 (0.62) | ERCC5FEN1RAB9AALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0751427-B1 | Image-dye-forming couplers and photographic elements containing them | EASTMAN KODAK CO (US) | 2001-03-28 | — | — | EP | claimed |
| EP-0751427-A1 | Image-dye-forming couplers and photographic elements containing them | KODAK LIMITED (GB) | 1997-01-02 | — | — | EP | claimed |
| CN-102321066-B | Method for producing aryl-aminopropanols | SALTIGO GMBH | 2014-07-23 | — | — | CN | disclosed |
| US-8293899-B2 | Ketone transfer hydrogenation of stereoisomerically enriched 3-heteroaryl-3-oxocarboxylic esters by reducing 3-heteroaryl-3-hydroxycarboxylic esters in the presence of a ruthenium-containing catalyst, an amine and formic acid and/or formates | LANXESS DEUTSCHLAND GMBH (DE) | 2012-10-23 | — | — | US | disclosed |
| CN-1445224-B | Process for preparing arylaminopropanols | SALTIGO GMBH | 2012-07-11 | — | — | CN | disclosed |
| CN-102321066-A | The method for preparing the arylamino propyl alcohol | SALTIGO GMBH | 2012-01-18 | — | — | CN | disclosed |
| US-7893281-B2 | Process for preparing arylaminopropanols | LANXESS DEUTSCHLAND GMBH (DE) | 2011-02-22 | — | — | US | disclosed |
| US-20090286997-A1 | PROCESS FOR PREPARING ARYLAMINOPROPANOLS | LANXESS DEUTSCHLAND GMBH (DE) | 2009-11-19 | — | — | US | disclosed |
| US-7582776-B2 | Process for preparing arylaminopropanols | LANXESS DEUTSCHLAND GMBH (DE) | 2009-09-01 | — | — | US | disclosed |
| EP-1346977-B1 | Method for producing aryl-aminopropanols | SALTIGO GMBH (DE) | 2009-07-22 | — | — | EP | disclosed |
| US-20080262247-A1 | Process for preparing arylaminopropanols | ECKERT MARKUS | 2008-10-23 | — | — | US | disclosed |
| US-20030225153-A1 | Process for preparing arylaminopropanols | LANXESS DEUTSCHLAND GMBH (DE) | 2003-12-04 | — | — | US | disclosed |
| US-20030225274-A1 | Process for reducing 3-heteroaryl-3-oxopropionic acid derivatives | LANXESS DEUTSCHLAND GMBH (DE) | 2003-12-04 | — | — | US | disclosed |
| CN-1445224-A | Process for preparing arylaminopropanols | BAYER AG (DE) | 2003-10-01 | — | — | CN | disclosed |
| EP-1346977-A1 | Method for producing aryl-aminopropanols | Bayer Aktiengesellschaft (DE) | 2003-09-24 | — | — | EP | disclosed |
| EP-1340746-A1 | Process for the reduction of 3-heteroaryl-3-oxo-propanoic acid derivatives | BAYER AG (DE) | 2003-09-03 | — | — | EP | disclosed |
| EP-0751427-B1 | Image-dye-forming couplers and photographic elements containing them | EASTMAN KODAK CO (US) | 2001-03-28 | — | — | EP | disclosed |
| US-5919969-A | MALONAMIDES | EASTMAN KODAK COMPANY (US) | 1999-07-06 | — | — | US | disclosed |
| EP-0751427-A1 | Image-dye-forming couplers and photographic elements containing them | KODAK LIMITED (GB) | 1997-01-02 | — | — | EP | disclosed |
| EP-0751427-A1 | Image-dye-forming couplers and photographic elements containing them | KODAK LIMITED (GB) | 1997-01-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030225153-A1 | Process for preparing arylaminopropanols | AHR, CYP1A1, CYP1A2 | ERCC5 2879/4885FEN1 1941/4885RAB9A 3297/4885 |
| US-20090286997-A1 | PROCESS FOR PREPARING ARYLAMINOPROPANOLS | AHR, CYP1A1, CYP1A2 | ERCC5 2879/4885FEN1 1941/4885RAB9A 3297/4885 |
| US-20080262247-A1 | Process for preparing arylaminopropanols | CYP1A1, CYP1A2, AHR | ERCC5 2967/4885FEN1 1728/4885RAB9A 3050/4885 |
| US-20030225274-A1 | Process for reducing 3-heteroaryl-3-oxopropionic acid derivatives | GRHPR, HPD, HAAO | ERCC5 1067/4885FEN1 1305/4885RAB9A 3428/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.