SCHEMBL28459884

SCHEMBL28459884

CC(=O)CC(=O)c1cccs1.[Nd]

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ERCC5 P28715 1/20 0.62
FEN1 P39748 1/20 0.62
ALDH1A1 P00352 4/20 0.62
NPC1 O15118 4/20 0.62
RAB9A P51151 4/20 0.62
LMNA P02545 3/20 0.62
MEN1 O00255 1/20 0.62
POLB P06746 1/20 0.62
KMT2A Q03164 1/20 0.62
GSK3B P49841 1/20 0.58
HPGD P15428 3/20 0.58
SMN1; SMN2 Q16637 1/20 0.58
CES2 O00748 1/20 0.52
CES1 P23141 1/20 0.52
HDAC1 Q13547 2/20 0.52
TSHR P16473 2/20 0.50
CTNNB1 P35222 1/20 0.50
WNT3A P56704 1/20 0.50
DAO P14920 1/20 0.50
PKM P14618 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1547840 0.98 ERCC5 (0.65) ERCC5FEN1ALDH1A1NPC1RAB9A
SCHEMBL711360 0.86 RAB9A (0.75) ERCC5FEN1ALDH1A1NPC1RAB9A
SCHEMBL18755474 0.81 ALDH1A1 (0.81) ERCC5FEN1ALDH1A1NPC1RAB9A
SCHEMBL4341460 0.80 ERCC5 (0.72) ERCC5FEN1ALDH1A1NPC1RAB9A
SCHEMBL1143695 0.79 ERCC5 (0.61) ERCC5FEN1ALDH1A1NPC1RAB9A
SCHEMBL1200312 0.79 LMNA (0.61) ERCC5FEN1ALDH1A1NPC1RAB9A
SCHEMBL6419377 0.79 ERCC5 (0.61) ERCC5FEN1ALDH1A1NPC1RAB9A
SCHEMBL1201437 0.78 ERCC5 (0.65) ERCC5FEN1ALDH1A1NPC1RAB9A
SCHEMBL1923026 0.78 ERCC5 (0.59) ERCC5FEN1ALDH1A1NPC1RAB9A
SCHEMBL1232758 0.78

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117178209-A Optical article, spectacle lens and spectacles 株式会社德山 2023-12-05 CN disclosed
CN-114846047-A Moisture-curable polyurethane composition and laminate 株式会社德山 2022-08-02 CN disclosed
CN-111727402-B Functional laminate and functional lens using same 株式会社德山 2022-07-15 CN disclosed
CN-109476973-B Adhesive composition, laminate, and optical article using the laminate 株式会社德山 2021-04-27 CN disclosed
CN-111727402-A Functional laminate and functional lens using same 株式会社德山 2020-09-29 CN disclosed