Sugi Predict

Sugi Predict / Compounds / SCHEMBL1201880

SCHEMBL1201880

SCHEMBL1201880

Cc1nc(Cl)c(Br)cc1[N+](=O)[O-]

nearest known ligand 0.45

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ CYP1A2 P05177 1/20 0.42
▸ CYP3A4 P08684 2/20 0.38
▸ ALDH1A1 P00352 2/20 0.38
▸ CTSB P07858 1/20 0.38
▸ TSHR P16473 2/20 0.37
▸ GPR35 Q9HC97 1/20 0.37
▸ GALR2 O43603 1/20 0.37
▸ LMNA P02545 1/20 0.37
▸ POLB P06746 1/20 0.37
▸ PDE7A Q13946 3/20 0.36
▸ PGK1 P00558 1/20 0.36
▸ MAPK1 P28482 1/20 0.36
▸ S1PR4 O95977 1/20 0.36
▸ CYP2D6 P10635 1/20 0.36
▸ PDE7B Q9NP56 2/20 0.36
▸ TDP1 Q9NUW8 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31484446 1.00 CYP1A2 (0.42) CYP1A2CYP3A4ALDH1A1CTSBTSHR
SCHEMBL31257509 0.87 CYP1A2 (0.41) CYP1A2CYP3A4ALDH1A1CTSBTSHR
SCHEMBL1558539 0.87 CYP1A2 (0.41) CYP1A2CYP3A4ALDH1A1CTSBTSHR
SCHEMBL38665481 0.85 CYP1A2 (0.44) CYP1A2CYP3A4ALDH1A1CTSBTSHR
SCHEMBL1200517 0.81 GPR35 (0.46) CYP1A2CYP3A4ALDH1A1CTSBTSHR
SCHEMBL20265347 0.81 TSHR (0.42) CYP3A4ALDH1A1TSHRGPR35GALR2
SCHEMBL14683926 0.81 CYP1A2 (0.44) CYP1A2CYP3A4ALDH1A1TSHRGPR35
SCHEMBL30515102 0.81 CYP1A2 (0.44) CYP1A2CYP3A4ALDH1A1TSHRGPR35
SCHEMBL23234456 0.80 ALDH1A1 (0.44) CYP3A4ALDH1A1CTSBTSHRPOLB
SCHEMBL16653792 0.80 CYP1A2 (0.41) CYP1A2CYP3A4ALDH1A1CTSBTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 133 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026106389-A1 NMT INHIBITOR AND USE THEREOF 주식회사 이노보테라퓨틱스 2026-05-21 — — WO disclosed
EP-4126879-B1 N-PHENYL SUBSTITUTED INDOLE DERIVATIVES AS MYT1 INHIBITORS FOR THE TREATMENT OF CANCER REPARE THERAPEUTICS INC (CA) 2026-01-21 — — EP disclosed
US-12435090-B2 Compounds, pharmaceutical compositions, and methods of preparing compounds and of their use REPARE THERAPEUTICS INC. (CA) 2025-10-07 — — US disclosed
US-12384780-B2 PARP1 inhibitors and uses thereof XINTHERA, INC. (US) 2025-08-12 — — US disclosed
US-12331057-B2 Modulators of alpha-1 antitrypsin VERTEX PHARMACEUTICALS INCORPORATED (US) 2025-06-17 — — US disclosed
CN-120081844-A PARP1 inhibitors and uses thereof 新特拉有限公司 2025-06-03 — — CN disclosed
CN-120058698-A Azetidine and pyrrolidine PARP1 inhibitors and uses thereof 新特拉有限公司 2025-05-30 — — CN disclosed
CN-118804916-B PARP1 inhibitors and uses thereof 新特拉有限公司 2025-04-01 — — CN disclosed
CN-118019532-B Azetidine and pyrrolidine PARP1 inhibitors and uses thereof 新特拉有限公司 2025-03-18 — — CN disclosed
WO-2025051157-A1 PYRIDINE-2(1H)-KETONE PRMT5-MTA INHIBITOR, AND PHARMACEUTICAL COMPOSITION AND USE THEREOF 赛诺哈勃药业（成都）有限公司 2025-03-13 — — WO disclosed
WO-2015089192-A1 INHIBITORS OF LYSINE SPECIFIC DEMETHYLASE-1 Quanticel Pharmaceuticals, Inc. (US) 2015-06-18 — — WO disclosed
US-20130338105-A1 IMINIPYRIDINE DERIVATIVES AND THEIR USES AS MICROBIOCIDES SYNGENTA CROP PROTECTION LLC (US) 2013-12-19 — — US disclosed
US-8513286-B2 Iminipyridine derivatives and their uses as microbiocides SYNGENTA CROP PROTECTION LLC (US) 2013-08-20 — — US disclosed
US-8513286-B2 Iminipyridine derivatives and their uses as microbiocides SYNGENTA CROP PROTECTION LLC (US) 2013-08-20 — — US disclosed
US-20110046088-A1 IMINIPYRIDINE DERIVATIVES AND THEIR USES AS MICROBIOCIDES SYNGENTA CROP PROTECTION, INC. (US) 2011-02-24 — — US disclosed
US-20110046088-A1 IMINIPYRIDINE DERIVATIVES AND THEIR USES AS MICROBIOCIDES SYNGENTA CROP PROTECTION, INC. (US) 2011-02-24 — — US disclosed
CN-101657423-A Iminopyridine derivatives and their use as microbicides SYNGENTA LTD 2010-02-24 — — CN disclosed
EP-2125734-A2 NOVEL MICROBIOCIDES Syngeta Participations AG (CH) 2009-12-02 — — EP disclosed
WO-2008101682-A2 IMINIPYRIDINE DERIVATIVES AND THEIR USES AS MICROBIOCIDES SYNGENTA PARTICIPATIONS AG (CH) 2008-08-28 — — WO disclosed
WO-2008101682-A2 IMINIPYRIDINE DERIVATIVES AND THEIR USES AS MICROBIOCIDES SYNGENTA PARTICIPATIONS AG (CH) 2008-08-28 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12384780-B2 PARP1 inhibitors and uses thereof PARP1, PARP11, PARP12 CYP1A2 3972/4885CYP3A4 3724/4885ALDH1A1 1913/4885
US-20110046088-A1 IMINIPYRIDINE DERIVATIVES AND THEIR USES AS MICROBIOCIDES CD14, MYADM, MPO CYP1A2 194/4885CYP3A4 139/4885ALDH1A1 153/4885
US-20130338105-A1 IMINIPYRIDINE DERIVATIVES AND THEIR USES AS MICROBIOCIDES CD14, MYADM, MPO CYP1A2 150/4885CYP3A4 107/4885ALDH1A1 171/4885
US-12435090-B2 Compounds, pharmaceutical compositions, and methods of preparing compounds and of their use PLK1, CSNK1A1, CSNK1G1 CYP1A2 4197/4885CYP3A4 3033/4885ALDH1A1 4093/4885
US-12331057-B2 Modulators of alpha-1 antitrypsin SERPINA2, SERPINC1, SERPINA3 CYP1A2 1268/4885CYP3A4 1833/4885ALDH1A1 477/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.