Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.43 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.43 |
| ▸ | GAPDH | P04406 | 1/20 | 0.43 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.42 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | FDPS | P14324 | 4/20 | 0.39 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | LAP3 | P28838 | 1/20 | 0.37 |
| ▸ | LCK | P06239 | 1/20 | 0.37 |
| ▸ | PPARD | Q03181 | 1/20 | 0.37 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.37 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27641377 | 0.84 | GPR84 (0.55) | MAPTGPR84FFAR1LCKPPARD | |
| SCHEMBL20143627 | 0.77 | CA1 (0.52) | MAPTSPHK1LMNAOPRM1FDPS | |
| SCHEMBL18100109 | 0.77 | CA2 (0.48) | MAPTSPHK1SPHK2LMNAFDPS | |
| SCHEMBL24933465 | 0.77 | CA1 (0.52) | MAPTSPHK1LMNAOPRM1FDPS | |
| SCHEMBL27473530 | 0.75 | CA2 (0.46) | LMNAOPRM1FDPSGPR84FFAR1 | |
| SCHEMBL22986849 | 0.75 | GPR84 (0.56) | MAPTSPHK1LMNAFDPSGPR84 | |
| SCHEMBL1310281 | 0.74 | GPR84 (0.48) | MAPTTRPA1DDAH1GAPDHFDPS | |
| SCHEMBL27381632 | 0.73 | CA2 (0.45) | SPHK1SPHK2LMNAFDPSGPR84 | |
| SCHEMBL27400263 | 0.73 | CA2 (0.45) | SPHK1SPHK2LMNAFDPSGPR84 | |
| SCHEMBL14079194 | 0.72 | GPR84 (0.52) | MAPTFDPSGPR84FFAR1LCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120220753-A1 | N-Terminal Dimerization Methods with Bis-Amindino Acid and Bis-Thioimidate Derivatives | THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE | 2012-08-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120220753-A1 | N-Terminal Dimerization Methods with Bis-Amindino Acid and Bis-Thioimidate Derivatives | ERBB2, MAX, DNPEP | MAPT 1722/4885TRPA1 4180/4885DDAH1 362/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.