Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 7/20 | 0.36 |
| ▸ | RAB9A | P51151 | 7/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.33 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | S100A4 | P26447 | 2/20 | 0.33 |
| ▸ | CDC25B | P30305 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14854458 | 0.81 | MKNK1 (0.41) | S100A4CDC25B | |
| SCHEMBL1203236 | 0.73 | CA1 (0.33) | MEN1KMT2AMAPK1GAA | |
| SCHEMBL1203340 | 0.69 | ALDH1A1 (0.47) | NPC1RAB9AMAPTPKMMEN1 | |
| SCHEMBL15122095 | 0.69 | KDM4E (0.48) | NPC1RAB9AMAPTPKMSMN1; SMN2 | |
| SCHEMBL8626370 | 0.69 | CRBN (0.41) | NPC1RAB9AMAPTKMT2ASMN1; SMN2 | |
| SCHEMBL3175492 | 0.69 | HPGD (0.44) | NPC1RAB9AMAPTMEN1KMT2A | |
| SCHEMBL27761013 | 0.68 | NPC1 (0.50) | NPC1RAB9AMAPTPKMMEN1 | |
| SCHEMBL30888262 | 0.68 | KDM4E (0.42) | NPC1RAB9AMAPTPKMSMN1; SMN2 | |
| SCHEMBL2630746 | 0.67 | PDE10A (0.41) | — | |
| SCHEMBL17257698 | 0.67 | NISCH (0.40) | NPC1RAB9AMAPTSMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110028318-A1 | HERBICIDAL COMPOUNDS BASED ON N-AZINYL-N'-PYRIDYLSULPHONYLUREAS | BAYER CROPSCIENCE AG (DE) | 2011-02-03 | — | — | US | disclosed |
| US-20110028318-A1 | HERBICIDAL COMPOUNDS BASED ON N-AZINYL-N'-PYRIDYLSULPHONYLUREAS | BAYER CROPSCIENCE AG (DE) | 2011-02-03 | — | — | US | disclosed |
| US-20110028318-A1 | HERBICIDAL COMPOUNDS BASED ON N-AZINYL-N'-PYRIDYLSULPHONYLUREAS | BAYER CROPSCIENCE AG (DE) | 2011-02-03 | — | — | US | disclosed |
| CN-101903379-A | Herbicidal compound based on N-azine group-N '-pyridyl sulfonylurea | BAYER CROPSCIENCE AG | 2010-12-01 | — | — | CN | disclosed |
| EP-2225234-A1 | HERBICIDAL COMPOUNDS BASED ON N-AZINYL-N'-PYRIDYLSULPHONYLUREAS | Bayer CropScience Aktiengesellschaft (DE) | 2010-09-08 | — | — | EP | disclosed |
| WO-2009080182-A1 | HERBICIDAL COMPOUNDS BASED ON N-AZINYL-N'-PYRIDYLSULPHONYLUREAS | BAYER CROPSCIENCE AG (DE) | 2009-07-02 | — | — | WO | disclosed |
| WO-2009080182-A1 | HERBICIDAL COMPOUNDS BASED ON N-AZINYL-N'-PYRIDYLSULPHONYLUREAS | BAYER CROPSCIENCE AG (DE) | 2009-07-02 | — | — | WO | disclosed |
| EP-2072512-A1 | Herbicide compounds based on N-Azinyl-N'-pyridylsulfonyl-ureas | Bayer CropScience AG (DE) | 2009-06-24 | — | — | EP | disclosed |
| EP-2072512-A1 | Herbicide compounds based on N-Azinyl-N'-pyridylsulfonyl-ureas | Bayer CropScience AG (DE) | 2009-06-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110028318-A1 | HERBICIDAL COMPOUNDS BASED ON N-AZINYL-N'-PYRIDYLSULPHONYLUREAS | DDT, AZI2, DNPH1 | NPC1 4644/4885RAB9A 1655/4885MAPT 4517/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.