SCHEMBL1203236

SCHEMBL1203236

NS(=O)(=O)c1ncccc1C1=NOCC1

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 9/20 0.33
CA2 P00918 9/20 0.33
CA9 Q16790 3/20 0.33
CA12 O43570 2/20 0.33
MKNK1 Q9BUB5 1/20 0.33
MKNK2 Q9HBH9 1/20 0.33
MAPK1 P28482 1/20 0.33
KMT2A Q03164 2/20 0.33
TDP2 O95551 1/20 0.33
NSD2 O96028 1/20 0.33
ABL1 P00519 1/20 0.33
PLCG1 P19174 1/20 0.33
CES1 P23141 1/20 0.33
PAX8 Q06710 1/20 0.33
RIN1 Q13671 1/20 0.33
MEN1 O00255 1/20 0.33
THRB P10828 1/20 0.33
BLM P54132 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
GAA P10253 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12893743 0.85 TDP2 (0.33) MKNK1MKNK2KMT2ATDP2NSD2
SCHEMBL3776593 0.78 CA1 (0.33) CA1CA2CA9CA12MAPK1
SCHEMBL14854458 0.78 MKNK1 (0.41) MKNK1MKNK2ABL1
SCHEMBL1576847 0.76 CA1 (0.32) CA1CA2CA9CA12MAPK1
SCHEMBL1202884 0.73 NPC1 (0.36) MAPK1KMT2AMEN1GAA
SCHEMBL8724464 0.69 KCNH2 (0.49) CA1CA2CA9CA12MAPK1
SCHEMBL9064045 0.68 EDNRA (0.41)
SCHEMBL700746 0.67 ALDH1A1 (0.44) KMT2AMEN1TDP1GAA
SCHEMBL8626370 0.67 CRBN (0.41) MAPK1KMT2ATDP1GAA
SCHEMBL3175492 0.67 HPGD (0.44) CA1CA2MAPK1KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110028318-A1 HERBICIDAL COMPOUNDS BASED ON N-AZINYL-N'-PYRIDYLSULPHONYLUREAS BAYER CROPSCIENCE AG (DE) 2011-02-03 US claimed
EP-2225234-A1 HERBICIDAL COMPOUNDS BASED ON N-AZINYL-N'-PYRIDYLSULPHONYLUREAS Bayer CropScience Aktiengesellschaft (DE) 2010-09-08 EP claimed
WO-2009080182-A1 HERBICIDAL COMPOUNDS BASED ON N-AZINYL-N'-PYRIDYLSULPHONYLUREAS BAYER CROPSCIENCE AG (DE) 2009-07-02 WO claimed
EP-2072512-A1 Herbicide compounds based on N-Azinyl-N'-pyridylsulfonyl-ureas Bayer CropScience AG (DE) 2009-06-24 EP claimed
US-20110028318-A1 HERBICIDAL COMPOUNDS BASED ON N-AZINYL-N'-PYRIDYLSULPHONYLUREAS BAYER CROPSCIENCE AG (DE) 2011-02-03 US disclosed
US-20110028318-A1 HERBICIDAL COMPOUNDS BASED ON N-AZINYL-N'-PYRIDYLSULPHONYLUREAS BAYER CROPSCIENCE AG (DE) 2011-02-03 US disclosed
US-20110028318-A1 HERBICIDAL COMPOUNDS BASED ON N-AZINYL-N'-PYRIDYLSULPHONYLUREAS BAYER CROPSCIENCE AG (DE) 2011-02-03 US disclosed
EP-2225234-A1 HERBICIDAL COMPOUNDS BASED ON N-AZINYL-N'-PYRIDYLSULPHONYLUREAS Bayer CropScience Aktiengesellschaft (DE) 2010-09-08 EP disclosed
WO-2009080182-A1 HERBICIDAL COMPOUNDS BASED ON N-AZINYL-N'-PYRIDYLSULPHONYLUREAS BAYER CROPSCIENCE AG (DE) 2009-07-02 WO disclosed
WO-2009080182-A1 HERBICIDAL COMPOUNDS BASED ON N-AZINYL-N'-PYRIDYLSULPHONYLUREAS BAYER CROPSCIENCE AG (DE) 2009-07-02 WO disclosed
EP-2072512-A1 Herbicide compounds based on N-Azinyl-N'-pyridylsulfonyl-ureas Bayer CropScience AG (DE) 2009-06-24 EP disclosed
EP-2072512-A1 Herbicide compounds based on N-Azinyl-N'-pyridylsulfonyl-ureas Bayer CropScience AG (DE) 2009-06-24 EP disclosed
EP-2072512-A1 Herbicide compounds based on N-Azinyl-N'-pyridylsulfonyl-ureas Bayer CropScience AG (DE) 2009-06-24 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110028318-A1 HERBICIDAL COMPOUNDS BASED ON N-AZINYL-N'-PYRIDYLSULPHONYLUREAS DDT, AZI2, DNPH1 CA1 4317/4885CA2 2675/4885CA9 3501/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.